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MAN2A2 and GIT1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
MAN2A2
GIT1
Description
mannosidase alpha class 2A member 2
GIT ArfGAP 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Integral Component Of Membrane
Mitochondrion
Cytosol
Focal Adhesion
Membrane
Calyx Of Held
Molecular Function
Alpha-mannosidase Activity
Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase Activity
Hydrolase Activity, Hydrolyzing N-glycosyl Compounds
Carbohydrate Binding
Metal Ion Binding
GTPase Activator Activity
Protein Binding
Protein-containing Complex Binding
Metal Ion Binding
Biological Process
Mannose Metabolic Process
Protein Glycosylation
N-glycan Processing
Protein Deglycosylation
Intramembranous Ossification
Brain Development
Locomotory Behavior
Regulation Of G Protein-coupled Receptor Signaling Pathway
Regulation Of Cytokinesis
Negative Regulation Of Interleukin-1 Beta Production
Positive Regulation Of GTPase Activity
Cell Redox Homeostasis
Negative Regulation Of Glycolytic Process
Ephrin Receptor Signaling Pathway
Neuron Development
Motor Learning
Cellular Response To Lipopolysaccharide
Presynaptic Modulation Of Chemical Synaptic Transmission
Negative Regulation Of Inflammatory Response To Wounding
Regulation Of Synaptic Vesicle Exocytosis
Pathways
Intra-Golgi traffic
Reactions specific to the complex N-glycan synthesis pathway
Ephrin signaling
Ephrin signaling
Activation of RAC1 downstream of NMDARs
Drugs
Diseases
GWAS
Attention deficit hyperactivity disorder (
18839057
)
Brain morphology (MOSTest) (
32665545
)
Schizophrenia (
25056061
29483656
)
Adult body size (
32376654
)
Brain morphology (MOSTest) (
32665545
)
Interacting Genes
6 interacting genes:
CHD3
ELP1
ENO3
GIT1
LUC7L2
VIM
52 interacting genes:
ARHGEF6
ARHGEF7
BARD1
C8orf33
CCDC113
CDC42
CENPU
CEP126
CHD3
DDX24
EIF6
ENTR1
GIT2
GRB2
GRK2
GRK3
GRK5
GRK6
HAP1
HMOX2
HTT
KIF1A
LAMTOR5
LPXN
LRIF1
MAN2A2
NEK2
PAK3
PCLO
PDPK1
PFDN1
PLCG1
PMF1
PPFIA1
PPFIA2
PPFIA3
PPFIA4
PTK2
PTPRZ1
PXN
RAN
RGS2
RIF1
SRC
SRRT
TAB1
TERF1
TGFB1I1
TRIB3
TXNDC9
WDR33
YWHAG
Entrez ID
4122
28964
HPRD ID
02994
06577
Ensembl ID
ENSG00000196547
ENSG00000108262
Uniprot IDs
P49641
Q59FC3
Q9Y2X7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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