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MIR17 and PUM1
Data Source:
BioGRID
(unspecified method)
MIR17
PUM1
Description
microRNA 17
pumilio RNA binding family member 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Mitochondrion
Extracellular Exosome
Extracellular Vesicle
P-body
Nucleoplasm
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
MiRNA Binding
Biological Process
Negative Regulation Of Systemic Arterial Blood Pressure
Outflow Tract Morphogenesis
Negative Regulation Of Gene Expression
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Low-density Lipoprotein Particle Clearance
Negative Regulation Of Toll-like Receptor Signaling Pathway
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Blood Pressure
Positive Regulation Of Fibroblast Proliferation
Positive Regulation Of Phagocytosis
Cellular Response To Lipopolysaccharide
Cellular Response To Hypoxia
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Negative Regulation Of Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Positive Regulation Of Connective Tissue Replacement Involved In Inflammatory Response Wound Healing
Positive Regulation Of Metalloendopeptidase Activity
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Apoptosome Assembly
Positive Regulation Of Pulmonary Blood Vessel Remodeling
Positive Regulation Of Smooth Muscle Hypertrophy
Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Negative Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport
Negative Regulation Of Cellular Senescence
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Spermatogenesis
Adult Locomotory Behavior
Posttranscriptional Regulation Of Gene Expression
Posttranscriptional Gene Silencing
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Regulation Of MRNA Stability
Stem Cell Differentiation
Regulation Of Cell Cycle
Regulation Of Chromosome Segregation
Regulation Of Gene Silencing By MiRNA
MRNA Destabilization
Positive Regulation Of RIG-I Signaling Pathway
Positive Regulation Of Gene Silencing By MiRNA
Pathways
Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Interacting Genes
84 interacting genes:
AIMP1
APOBEC3B
ATXN2L
C1QBP
CELF1
CPSF6
CPSF7
CRTAP
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LARS1
LIN28A
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT21
NUFIP2
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUM1
PUM2
PURA
QARS1
RARS1
RBFOX2
RBM14
RBM4
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
TRMT1L
UPF1
USP36
UTP20
YBX1
YBX2
YBX3
ZNF346
47 interacting genes:
ATXN1
EIF5
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR143
MIR145
MIR15B
MIR17
MIR18B
MIR199A1
MIR199A2
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR25
MIR29A
MIR29C
MIR34A
MIR7-1
MIR9-3
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PRR12
SMAD1
Entrez ID
406952
9698
HPRD ID
06230
Ensembl ID
ENSG00000284536
ENSG00000134644
Uniprot IDs
Q14671
PDB IDs
1IB2
1M8W
1M8X
1M8Y
1M8Z
2YJY
3BSB
3BSX
3Q0L
3Q0M
3Q0N
3Q0O
3Q0P
5YKH
5YKI
Enriched GO Terms of Interacting Partners
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