MIR17 and CRTAP

Data Source:
BioGRID (unspecified method)

		MIR17	CRTAP
Description		microRNA 17	cartilage associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Extracellular Exosome Extracellular Vesicle	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Protein-containing Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	Protein Binding Collagen Binding
	Biological Process	Negative Regulation Of Systemic Arterial Blood Pressure Outflow Tract Morphogenesis Negative Regulation Of Gene Expression Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Low-density Lipoprotein Particle Clearance Negative Regulation Of Toll-like Receptor Signaling Pathway Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Blood Pressure Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Phagocytosis Cellular Response To Lipopolysaccharide Cellular Response To Hypoxia Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Positive Regulation Of Metalloendopeptidase Activity Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Apoptosome Assembly Positive Regulation Of Pulmonary Blood Vessel Remodeling Positive Regulation Of Smooth Muscle Hypertrophy Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport Negative Regulation Of Cellular Senescence Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Spermatogenesis Peptidyl-proline Hydroxylation To 3-hydroxy-L-proline Collagen Fibril Organization Protein Stabilization Chaperone-mediated Protein Folding Negative Regulation Of Post-translational Protein Modification
Pathways			Collagen biosynthesis and modifying enzymes
Drugs
Diseases			Osteogenesis imperfecta
GWAS			Asthma ( 31959851 31619474) Major depressive disorder ( 29317602) Multiple sclerosis ( 31604244) Refractive error ( 32231278) Retinal detachment or retinal break ( 31816047)
Interacting Genes		84 interacting genes: AIMP1 APOBEC3B ATXN2L C1QBP CELF1 CPSF6 CPSF7 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRMT1L UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZNF346	24 interacting genes: MIR1-1 MIR10B MIR128-1 MIR138-2 MIR140 MIR16-1 MIR16-2 MIR17 MIR18A MIR199A2 MIR19A MIR19B1 MIR200B MIR200C MIR20A MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIRLET7B MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I
Entrez ID		406952	10491
HPRD ID			16110
Ensembl ID		ENSG00000284536	ENSG00000170275
Uniprot IDs			O75718
PDB IDs
Enriched GO Terms of Interacting Partners?
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