PUM1 and PRR12

Data Source:
BioGRID (two hybrid)

		PUM1	PRR12
Description		pumilio RNA binding family member 1	proline rich 12
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule	Nucleus Postsynaptic Density Neuron Projection
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding MiRNA Binding
	Biological Process	Spermatogenesis Adult Locomotory Behavior Posttranscriptional Regulation Of Gene Expression Posttranscriptional Gene Silencing Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of MRNA Stability Stem Cell Differentiation Regulation Of Cell Cycle Regulation Of Chromosome Segregation Regulation Of Gene Silencing By MiRNA MRNA Destabilization Positive Regulation Of RIG-I Signaling Pathway Positive Regulation Of Gene Silencing By MiRNA
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Fibrinogen levels ( 26561523) HDL cholesterol levels ( 32203549) Schizophrenia ( 25056061 29483656) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655)
Interacting Genes		47 interacting genes: ATXN1 EIF5 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR143 MIR145 MIR15B MIR17 MIR18B MIR199A1 MIR199A2 MIR19B1 MIR19B2 MIR200A MIR200B MIR206 MIR20A MIR20B MIR21 MIR214 MIR25 MIR29A MIR29C MIR34A MIR7-1 MIR9-3 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PRR12 SMAD1	2 interacting genes: FASN PUM1
Entrez ID		9698	57479
HPRD ID		06230	19620
Ensembl ID		ENSG00000134644	ENSG00000126464
Uniprot IDs		Q14671	Q9ULL5
PDB IDs		1IB2 1M8W 1M8X 1M8Y 1M8Z 2YJY 3BSB 3BSX 3Q0L 3Q0M 3Q0N 3Q0O 3Q0P 5YKH 5YKI
Enriched GO Terms of Interacting Partners?
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