PUM1 and MIR20A

Data Source:
BioGRID (unspecified method)

		PUM1	MIR20A
Description		pumilio RNA binding family member 1	microRNA 20a
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule	Extracellular Space Extracellular Vesicle
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding MiRNA Binding	RNA Polymerase II Complex Binding MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Spermatogenesis Adult Locomotory Behavior Posttranscriptional Regulation Of Gene Expression Posttranscriptional Gene Silencing Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of MRNA Stability Stem Cell Differentiation Regulation Of Cell Cycle Regulation Of Chromosome Segregation Regulation Of Gene Silencing By MiRNA MRNA Destabilization Positive Regulation Of RIG-I Signaling Pathway Positive Regulation Of Gene Silencing By MiRNA	Outflow Tract Morphogenesis Negative Regulation Of Protein Kinase Activity Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Interleukin-17 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Cell Adhesion Molecule Production Cellular Response To Lipopolysaccharide Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of P38MAPK Cascade Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Cardioblast Proliferation Positive Regulation Of Pulmonary Blood Vessel Remodeling
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Interacting Genes		47 interacting genes: ATXN1 EIF5 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR143 MIR145 MIR15B MIR17 MIR18B MIR199A1 MIR199A2 MIR19B1 MIR19B2 MIR200A MIR200B MIR206 MIR20A MIR20B MIR21 MIR214 MIR25 MIR29A MIR29C MIR34A MIR7-1 MIR9-3 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PRR12 SMAD1	73 interacting genes: AIMP2 APOBEC3B C1QBP CRTAP DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DZIP3 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC LSM10 LSM11 MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SFPQ SUGP2 SYNCRIP TAF15 TIAL1 TRA2A TRA2B UPF1 UTP20 YBX1 YBX3 ZNF346
Entrez ID		9698	406982
HPRD ID		06230
Ensembl ID		ENSG00000134644	ENSG00000283762
Uniprot IDs		Q14671
PDB IDs		1IB2 1M8W 1M8X 1M8Y 1M8Z 2YJY 3BSB 3BSX 3Q0L 3Q0M 3Q0N 3Q0O 3Q0P 5YKH 5YKI
Enriched GO Terms of Interacting Partners?
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