NHLH1 and CCT7

Data Source:
BioGRID (two hybrid)

		NHLH1	CCT7
Description		nescient helix-loop-helix 1	chaperonin containing TCP1 subunit 7
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytoplasm Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Exosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Binding ATP Binding Identical Protein Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways			Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS			General cognitive ability ( 29844566)
Interacting Genes		11 interacting genes: CCT7 CENPP CSRP3 HIVEP1 INO80E LMO1 LMO2 LMO4 PIM1 PSME2 TCF3	22 interacting genes: ANXA1 ANXA7 APP ATP5F1C CDKN1A CEBPE CRMP1 DNM2 EEF1G KAT5 KRAS LINC01554 MED31 NHLH1 NKX3-1 PRPF40A RAP1B RCC1 SUMO4 TCP1 WBP2 ZNRD2
Entrez ID		4807	10574
HPRD ID		01212	06896
Ensembl ID		ENSG00000171786	ENSG00000135624
Uniprot IDs		Q02575 Q5T203	Q99832
PDB IDs			6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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