NHLH1 and CSRP3

Data Source:
HPRD (in vitro, two hybrid)

		NHLH1	CSRP3
Description		nescient helix-loop-helix 1	cysteine and glycine rich protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Cytoplasm Cytoskeleton Z Disc
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Actin Binding Protein Binding Structural Constituent Of Muscle Telethonin Binding Identical Protein Binding Actinin Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of The Force Of Heart Contraction Cardiac Muscle Hypertrophy Cellular Calcium Ion Homeostasis Inflammatory Response Skeletal Muscle Tissue Development Insulin Receptor Signaling Pathway Actin Cytoskeleton Organization T-tubule Organization Protein Localization To Organelle Detection Of Muscle Stretch Glucose Homeostasis Sarcomere Organization Positive Regulation Of Transcription By RNA Polymerase II Cardiac Muscle Tissue Development Cardiac Myofibril Assembly Cardiac Muscle Contraction Muscle Tissue Development Protein Kinase C Signaling Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases			Hypertrophic cardiomyopathy (HCM)
GWAS			Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Mosquito bite size ( 28199695) Red blood cell count ( 32888494 27863252)
Interacting Genes		11 interacting genes: CCT7 CENPP CSRP3 HIVEP1 INO80E LMO1 LMO2 LMO4 PIM1 PSME2 TCF3	11 interacting genes: ACTN1 FHL1 HDAC4 LDHD LIMS1 MYF6 MYOD1 MYOG NHLH1 RIN3 SPTB
Entrez ID		4807	8048
HPRD ID		01212	07525
Ensembl ID		ENSG00000171786	ENSG00000129170
Uniprot IDs		Q02575 Q5T203	A2TDB8 P50461
PDB IDs			2O10 2O13
Enriched GO Terms of Interacting Partners?
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