MCCD1 and P4HA3

Data Source:
BioGRID (two hybrid)

		MCCD1	P4HA3
Description		mitochondrial coiled-coil domain 1	prolyl 4-hydroxylase subunit alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding
	Biological Process		Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Pathways			Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		AIDS progression ( 19115949) Asthma ( 31619474 29273806) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cervical cancer ( 28806749) Inflammatory bowel disease ( 28067908) Lymphocyte counts ( 32888494) Malaria ( 31844061) Monocyte count ( 32888494) Ulcerative colitis ( 28067908)	Hippocampal atrophy ( 25625606)
Interacting Genes		26 interacting genes: BEX3 BFSP2 CAB39 COX5B FNDC3B KANK2 KRT26 KYNU LMO4 LSM1 MEIS2 MGAT5B MKRN3 MX1 MYL7 P4HA3 PIH1D2 PPP1R16A PRR35 QARS1 RIPPLY1 USHBP1 USP20 ZNF417 ZNF587 ZNF765	50 interacting genes: ACOT8 ADRA2C ANAPC11 ATN1 B9D2 BAG4 BLOC1S2 C1orf112 C1QTNF2 CERCAM CKMT2 CLPP CT55 CTAG1A CTAG1B CTNNBIP1 DTNBP1 FAM136A GGA3 GPSM3 HGS KRTAP19-5 KRTAP6-1 KRTAP8-1 LRP2BP MAGEA2 MAGEA2B MAGEC2 MCCD1 MEOX2 MSRA NDN NICN1 NUTM1 OIP5 P4HB PROP1 PSMB4 RBFOX1 RUSC1 SCARA5 SERTAD1 SERTAD3 STMN3 TLE5 TOX2 VPS37C WDR62 ZBTB7B ZC3H12A
Entrez ID		401250	283208
HPRD ID		17470	16413
Ensembl ID		ENSG00000204511	ENSG00000149380
Uniprot IDs		A0A1U9X802 P59942	Q7Z4N8
PDB IDs
Enriched GO Terms of Interacting Partners?
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