P4HA3 and MCCD1

Data Source:
BioGRID (two hybrid)

		P4HA3	MCCD1
Description		prolyl 4-hydroxylase subunit alpha 3	mitochondrial coiled-coil domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Mitochondrion
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding	Protein Binding
	Biological Process	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Pathways		Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Hippocampal atrophy ( 25625606)	AIDS progression ( 19115949) Asthma ( 31619474 29273806) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cervical cancer ( 28806749) Inflammatory bowel disease ( 28067908) Lymphocyte counts ( 32888494) Malaria ( 31844061) Monocyte count ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		50 interacting genes: ACOT8 ADRA2C ANAPC11 ATN1 B9D2 BAG4 BLOC1S2 C1orf112 C1QTNF2 CERCAM CKMT2 CLPP CT55 CTAG1A CTAG1B CTNNBIP1 DTNBP1 FAM136A GGA3 GPSM3 HGS KRTAP19-5 KRTAP6-1 KRTAP8-1 LRP2BP MAGEA2 MAGEA2B MAGEC2 MCCD1 MEOX2 MSRA NDN NICN1 NUTM1 OIP5 P4HB PROP1 PSMB4 RBFOX1 RUSC1 SCARA5 SERTAD1 SERTAD3 STMN3 TLE5 TOX2 VPS37C WDR62 ZBTB7B ZC3H12A	26 interacting genes: BEX3 BFSP2 CAB39 COX5B FNDC3B KANK2 KRT26 KYNU LMO4 LSM1 MEIS2 MGAT5B MKRN3 MX1 MYL7 P4HA3 PIH1D2 PPP1R16A PRR35 QARS1 RIPPLY1 USHBP1 USP20 ZNF417 ZNF587 ZNF765
Entrez ID		283208	401250
HPRD ID		16413	17470
Ensembl ID		ENSG00000149380	ENSG00000204511
Uniprot IDs		Q7Z4N8	A0A1U9X802 P59942
PDB IDs
Enriched GO Terms of Interacting Partners?
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