P4HA3 and NICN1

Data Source:
BioGRID (two hybrid)

		P4HA3	NICN1
Description		prolyl 4-hydroxylase subunit alpha 3	nicolin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Nucleoplasm Microtubule
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding	Protein Binding
	Biological Process	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Pathways		Collagen biosynthesis and modifying enzymes	Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS		Hippocampal atrophy ( 25625606)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Depressive symptoms (binary sum-score) ( 31530331) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Mood instability ( 31168069) Red cell distribution width ( 28957414) Refractive error ( 32231278) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		50 interacting genes: ACOT8 ADRA2C ANAPC11 ATN1 B9D2 BAG4 BLOC1S2 C1orf112 C1QTNF2 CERCAM CKMT2 CLPP CT55 CTAG1A CTAG1B CTNNBIP1 DTNBP1 FAM136A GGA3 GPSM3 HGS KRTAP19-5 KRTAP6-1 KRTAP8-1 LRP2BP MAGEA2 MAGEA2B MAGEC2 MCCD1 MEOX2 MSRA NDN NICN1 NUTM1 OIP5 P4HB PROP1 PSMB4 RBFOX1 RUSC1 SCARA5 SERTAD1 SERTAD3 STMN3 TLE5 TOX2 VPS37C WDR62 ZBTB7B ZC3H12A	11 interacting genes: ATP6V0D2 NFKBID P4HA3 POGZ RUSC1 TENT5B TLX3 TRAPPC2 TRAPPC2B TTC9C ZNF77
Entrez ID		283208	84276
HPRD ID		16413	17631
Ensembl ID		ENSG00000149380	ENSG00000145029
Uniprot IDs		Q7Z4N8	B2R7Q3 Q9BSH3
PDB IDs
Enriched GO Terms of Interacting Partners?
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