P4HA3 and MAGEC2

Data Source:
BioGRID (two hybrid)

		P4HA3	MAGEC2
Description		prolyl 4-hydroxylase subunit alpha 3	MAGE family member C2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Nucleoplasm Cytosol
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline	Cellular Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity
Pathways		Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Hippocampal atrophy ( 25625606)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Non-response to bupropion and depression ( 27622933)
Interacting Genes		50 interacting genes: ACOT8 ADRA2C ANAPC11 ATN1 B9D2 BAG4 BLOC1S2 C1orf112 C1QTNF2 CERCAM CKMT2 CLPP CT55 CTAG1A CTAG1B CTNNBIP1 DTNBP1 FAM136A GGA3 GPSM3 HGS KRTAP19-5 KRTAP6-1 KRTAP8-1 LRP2BP MAGEA2 MAGEA2B MAGEC2 MCCD1 MEOX2 MSRA NDN NICN1 NUTM1 OIP5 P4HB PROP1 PSMB4 RBFOX1 RUSC1 SCARA5 SERTAD1 SERTAD3 STMN3 TLE5 TOX2 VPS37C WDR62 ZBTB7B ZC3H12A	13 interacting genes: MNAT1 P4HA3 PBX3 PCGF6 RBX1 RNF166 SSX1 SSX2 TAF9 TRAF4 TRIM8 UBR3 ZMYND11
Entrez ID		283208	51438
HPRD ID		16413	06632
Ensembl ID		ENSG00000149380	ENSG00000046774
Uniprot IDs		Q7Z4N8	Q9UBF1
PDB IDs
Enriched GO Terms of Interacting Partners?
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