P4HA3 and MAGEA2B

Data Source:
BioGRID (two hybrid)

		P4HA3	MAGEA2B
Description		prolyl 4-hydroxylase subunit alpha 3	MAGE family member A2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Nucleus PML Body
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding	Protein Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding Repressing Transcription Factor Binding
	Biological Process	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Sumoylation Cellular Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction By P53 Class Mediator Cellular Senescence Negative Regulation Of Protein Acetylation
Pathways		Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Hippocampal atrophy ( 25625606)
Interacting Genes		50 interacting genes: ACOT8 ADRA2C ANAPC11 ATN1 B9D2 BAG4 BLOC1S2 C1orf112 C1QTNF2 CERCAM CKMT2 CLPP CT55 CTAG1A CTAG1B CTNNBIP1 DTNBP1 FAM136A GGA3 GPSM3 HGS KRTAP19-5 KRTAP6-1 KRTAP8-1 LRP2BP MAGEA2 MAGEA2B MAGEC2 MCCD1 MEOX2 MSRA NDN NICN1 NUTM1 OIP5 P4HB PROP1 PSMB4 RBFOX1 RUSC1 SCARA5 SERTAD1 SERTAD3 STMN3 TLE5 TOX2 VPS37C WDR62 ZBTB7B ZC3H12A	24 interacting genes: ACSM1 ANKRD45 BEX1 BEX2 CCDC185 CEP57 CEP57L1 COQ4 COX7C DYNLRB1 KRT8P12 MBD3 NTAQ1 P4HA3 PHKG2 POLL PSMC1 SEPTIN5 SMARCD1 TNIP3 TRIM28 TRIM31 TUBB ZNF655
Entrez ID		283208	266740
HPRD ID		16413	14347
Ensembl ID		ENSG00000149380	ENSG00000183305
Uniprot IDs		Q7Z4N8	A0A024RC17 P43356
PDB IDs
Enriched GO Terms of Interacting Partners?
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