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INCA1 and BAG3
Data Source:
BioGRID
(two hybrid)
INCA1
BAG3
Description
inhibitor of CDK, cyclin A1 interacting protein 1
BAG cochaperone 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Body
Stress Fiber
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Aggresome
Z Disc
Neuron Projection
Chaperone Complex
Molecular Function
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Protein Binding
Cyclin Binding
Identical Protein Binding
Protein-containing Complex Binding
Adenyl-nucleotide Exchange Factor Activity
Protein Binding
Heat Shock Protein Binding
Protein-containing Complex Binding
Cadherin Binding
Dynein Intermediate Chain Binding
Chaperone Binding
Biological Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Apoptotic Signaling Pathway
Autophagosome Assembly
Protein Folding
Brain Development
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Spinal Cord Development
Cellular Response To Heat
Cellular Response To Unfolded Protein
Positive Regulation Of Protein Import Into Nucleus
Negative Regulation Of Apoptotic Process
Muscle Cell Cellular Homeostasis
Positive Regulation Of Protein Export From Nucleus
Regulation Of Catalytic Activity
Protein Stabilization
Chaperone-mediated Autophagy
Aggresome Assembly
Cellular Response To Mechanical Stimulus
Chaperone-mediated Protein Transport
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Protein Transport Along Microtubule
Regulation Of Cellular Response To Heat
Negative Regulation Of Protein Targeting To Mitochondrion
Positive Regulation Of Aggrephagy
Pathways
Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS
Intraocular pressure (
29235454
)
Obesity-related traits (
23251661
)
Diastolic blood pressure (
27841878
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Heart failure (
31919418
)
Idiopathic dilated cardiomyopathy (
21459883
)
Left ventricular ejection fraction (
32382064
32605384
)
Left ventricular end-systolic volume (
32382064
)
Parkinson's disease (
32201043
27182965
28892059
)
Parkinson's disease or first degree relation to individual with Parkinson's disease (
31701892
)
Interacting Genes
236 interacting genes:
ABI2
ACY3
AKAP8L
ANKRD28
ARMC7
ASPSCR1
ATG5
ATP6V0D2
ATPAF2
BAG3
BANF2
BOLA3
BPIFA1
C10orf55
C19orf54
C1orf35
C1orf50
C1orf56
C22orf39
CABP5
CCBE1
CCDC57
CCDC78
CCNA1
CDA
CDC23
CDK18
CDK2
CDK4
CDKN1A
CDKN2B
CDKN2D
CEP72
CHCHD2
CHCHD5
CHRD
CINP
CKS1B
CLIC3
CLK3
COL8A1
CPSF1
CSDC2
CSTF2
CTNNBIP1
CTTNBP2
CYSRT1
DAZAP2
DEF6
DMRT3
DMRTB1
DOK4
DPH7
DUSP13
EFEMP2
EMD
EPHB6
EXOSC8
FAAP20
FAIM
FEM1A
FGF16
FHL2
FMR1
FRS3
GEM
GEMIN2
GRB2
GRXCR1
GSTO2
GTF2H5
GTPBP3
GYS1
HAUS1
HCK
HDAC4
HEMK1
HENMT1
HNRNPF
HOMER3
HOXA1
HR
HSD17B14
HYI
IL36RN
ILF2
KCTD7
KCTD9
KIAA1217
KIR2DL4
KLHL26
KLHL42
KRT33B
KRT5
KRT75
KRTAP15-1
KRTAP19-1
KRTAP19-5
KRTAP19-6
KRTAP5-6
KRTAP6-2
KRTAP6-3
KRTAP9-3
LENG8
LGALS3
LHX3
LMNTD2
LMO2
LMO3
LSM3
LYPLA2
MAD2L2
MAGED4B
MAGOHB
MALSU1
MARF1
MARK1
MATN3
MBLAC1
METAP1
MPP1
MSRB1
MTMR9
NATD1
NCK2
NDUFAF3
NEDD9
NEIL2
NEK6
NFKBID
NHSL2
NME7
NMRK1
NPAS2
NTAQ1
NUBP2
NUDT16L1
NUDT22
OR6B1
OSGIN1
PADI3
PATE1
PCSK5
PCYT2
PDP1
PEF1
PFDN5
PHF1
PLA2G10
PLSCR3
POLR1C
POLR3C
POP5
POU4F2
PPP1R32
PRPH
PSMB2
PSMB8
PTGER3
R3HDM2
RAB5C
RALB
RAMAC
RBPMS
RECK
RFC3
RIPPLY3
RNF26
SAP18
SCNM1
SEC14L4
SHFL
SLC22A18AS
SMG9
SMUG1
SNRPB
SPAG8
SPG21
SPOUT1
SPRY1
STAMBPL1
STK16
STT3B
SUOX
TBC1D7
TCL1A
TEAD4
TEKT4
TEX12
TFAP2A
TFAP2D
TFAP4
TFG
THAP6
THRSP
TIAL1
TPRX1
TRAPPC2
TRAPPC2B
TRAPPC6A
TRIB3
TRIM26
TRIM55
TRIM63
TRIM68
TRIP13
TRIP6
TSEN15
TSG101
TSSK3
TSTD2
TXNDC17
UBASH3B
UBE2D4
UBE2Z
UBTD2
UBXN2B
UFM1
UFSP1
VEZF1
VGLL3
VPS26C
VPS28
WWOX
YIPF3
YOD1
ZDHHC24
ZFAND3
ZMYND12
ZMYND19
ZNF205-AS1
ZNF32
ZNF446
ZNF747
ZNF765
ZNRD2
75 interacting genes:
ACD
ARRDC3
ATN1
ATXN7L2
BAIAP2L1
BCL2
CRYAB
CTDSP1
CYSRT1
CYSTM1
DAZAP2
DNM2
DTX3
DVL1
DVL2
DYNLT1
EGR4
EYA2
FAM168B
FAM189A2
FBXO7
FOXD4L1
GGN
GLIS3
HELT
HSPA1A
HSPA5
HSPA8
HSPB1
HSPB2
HSPB2-C11orf52
HSPB7
HSPB8
INCA1
LENG8
LITAF
LRRK1
LRRK2
MAGED1
MDFI
MRPL38
NIBAN3
NOTO
NR1H3
PDE9A
PDLIM7
PIH1D2
PLA2G10
PLCG1
PLEKHB1
POT1
PRDM6
PRKAR1B
PRR34
PTPN21
RUNX1
SF3B4
SHISA6
SIAH1
SPRY2
SRPK2
TBC1D3B
TBC1D3G
TINF2
TMEM174
TNK2
TP53BP2
TRIB3
TRIM27
TRIP6
TSC1
UNKL
VPS37B
WBP2
WNK1
Entrez ID
388324
9531
HPRD ID
17150
04860
Ensembl ID
ENSG00000196388
ENSG00000151929
Uniprot IDs
Q0VD86
O95817
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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