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BAG3 and MRPL38
Data Source:
BioGRID
(two hybrid)
BAG3
MRPL38
Description
BAG cochaperone 3
mitochondrial ribosomal protein L38
Image
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Aggresome
Z Disc
Neuron Projection
Chaperone Complex
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Large Ribosomal Subunit
Molecular Function
Adenyl-nucleotide Exchange Factor Activity
Protein Binding
Heat Shock Protein Binding
Protein-containing Complex Binding
Cadherin Binding
Dynein Intermediate Chain Binding
Chaperone Binding
Protein Binding
Biological Process
Autophagosome Assembly
Protein Folding
Brain Development
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Spinal Cord Development
Cellular Response To Heat
Cellular Response To Unfolded Protein
Positive Regulation Of Protein Import Into Nucleus
Negative Regulation Of Apoptotic Process
Muscle Cell Cellular Homeostasis
Positive Regulation Of Protein Export From Nucleus
Regulation Of Catalytic Activity
Protein Stabilization
Chaperone-mediated Autophagy
Aggresome Assembly
Cellular Response To Mechanical Stimulus
Chaperone-mediated Protein Transport
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Protein Transport Along Microtubule
Regulation Of Cellular Response To Heat
Negative Regulation Of Protein Targeting To Mitochondrion
Positive Regulation Of Aggrephagy
Mitochondrial Translational Elongation
Mitochondrial Translational Termination
Pathways
Regulation of HSF1-mediated heat shock response
Mitochondrial translation initiation
Mitochondrial translation elongation
Mitochondrial translation elongation
Mitochondrial translation termination
Drugs
Diseases
GWAS
Diastolic blood pressure (
27841878
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Heart failure (
31919418
)
Idiopathic dilated cardiomyopathy (
21459883
)
Left ventricular ejection fraction (
32382064
32605384
)
Left ventricular end-systolic volume (
32382064
)
Parkinson's disease (
32201043
27182965
28892059
)
Parkinson's disease or first degree relation to individual with Parkinson's disease (
31701892
)
Interacting Genes
75 interacting genes:
ACD
ARRDC3
ATN1
ATXN7L2
BAIAP2L1
BCL2
CRYAB
CTDSP1
CYSRT1
CYSTM1
DAZAP2
DNM2
DTX3
DVL1
DVL2
DYNLT1
EGR4
EYA2
FAM168B
FAM189A2
FBXO7
FOXD4L1
GGN
GLIS3
HELT
HSPA1A
HSPA5
HSPA8
HSPB1
HSPB2
HSPB2-C11orf52
HSPB7
HSPB8
INCA1
LENG8
LITAF
LRRK1
LRRK2
MAGED1
MDFI
MRPL38
NIBAN3
NOTO
NR1H3
PDE9A
PDLIM7
PIH1D2
PLA2G10
PLCG1
PLEKHB1
POT1
PRDM6
PRKAR1B
PRR34
PTPN21
RUNX1
SF3B4
SHISA6
SIAH1
SPRY2
SRPK2
TBC1D3B
TBC1D3G
TINF2
TMEM174
TNK2
TP53BP2
TRIB3
TRIM27
TRIP6
TSC1
UNKL
VPS37B
WBP2
WNK1
21 interacting genes:
ARHGAP9
BAG3
BEX2
CCDC120
CENATAC
CSNK2A1
DOCK8
ENKD1
ERCC6
ERG28
GADD45GIP1
GOLGA6A
HSPB3
LONRF1
MKRN3
MRPL18
MYOZ3
PPP1R18
PRIM1
RALY
TSEN54
Entrez ID
9531
64978
HPRD ID
04860
14758
Ensembl ID
ENSG00000151929
ENSG00000204316
Uniprot IDs
O95817
Q96DV4
PDB IDs
3J7Y
3J9M
5OOL
5OOM
6I9R
6NU2
6NU3
6VLZ
6VMI
6ZS9
6ZSA
6ZSB
6ZSC
6ZSD
6ZSE
6ZSG
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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