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INCA1 and HAUS1
Data Source:
BioGRID
(two hybrid)
INCA1
HAUS1
Description
inhibitor of CDK, cyclin A1 interacting protein 1
HAUS augmin like complex subunit 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Body
Spindle Pole
Centrosome
Cytosol
HAUS Complex
Mitotic Spindle Microtubule
Molecular Function
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Protein Binding
Cyclin Binding
Identical Protein Binding
Protein-containing Complex Binding
Molecular_function
Protein Binding
Biological Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Apoptotic Signaling Pathway
G2/M Transition Of Mitotic Cell Cycle
Centrosome Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Spindle Assembly
Cell Division
Ciliary Basal Body-plasma Membrane Docking
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Intraocular pressure (
29235454
)
Obesity-related traits (
23251661
)
Interacting Genes
236 interacting genes:
ABI2
ACY3
AKAP8L
ANKRD28
ARMC7
ASPSCR1
ATG5
ATP6V0D2
ATPAF2
BAG3
BANF2
BOLA3
BPIFA1
C10orf55
C19orf54
C1orf35
C1orf50
C1orf56
C22orf39
CABP5
CCBE1
CCDC57
CCDC78
CCNA1
CDA
CDC23
CDK18
CDK2
CDK4
CDKN1A
CDKN2B
CDKN2D
CEP72
CHCHD2
CHCHD5
CHRD
CINP
CKS1B
CLIC3
CLK3
COL8A1
CPSF1
CSDC2
CSTF2
CTNNBIP1
CTTNBP2
CYSRT1
DAZAP2
DEF6
DMRT3
DMRTB1
DOK4
DPH7
DUSP13
EFEMP2
EMD
EPHB6
EXOSC8
FAAP20
FAIM
FEM1A
FGF16
FHL2
FMR1
FRS3
GEM
GEMIN2
GRB2
GRXCR1
GSTO2
GTF2H5
GTPBP3
GYS1
HAUS1
HCK
HDAC4
HEMK1
HENMT1
HNRNPF
HOMER3
HOXA1
HR
HSD17B14
HYI
IL36RN
ILF2
KCTD7
KCTD9
KIAA1217
KIR2DL4
KLHL26
KLHL42
KRT33B
KRT5
KRT75
KRTAP15-1
KRTAP19-1
KRTAP19-5
KRTAP19-6
KRTAP5-6
KRTAP6-2
KRTAP6-3
KRTAP9-3
LENG8
LGALS3
LHX3
LMNTD2
LMO2
LMO3
LSM3
LYPLA2
MAD2L2
MAGED4B
MAGOHB
MALSU1
MARF1
MARK1
MATN3
MBLAC1
METAP1
MPP1
MSRB1
MTMR9
NATD1
NCK2
NDUFAF3
NEDD9
NEIL2
NEK6
NFKBID
NHSL2
NME7
NMRK1
NPAS2
NTAQ1
NUBP2
NUDT16L1
NUDT22
OR6B1
OSGIN1
PADI3
PATE1
PCSK5
PCYT2
PDP1
PEF1
PFDN5
PHF1
PLA2G10
PLSCR3
POLR1C
POLR3C
POP5
POU4F2
PPP1R32
PRPH
PSMB2
PSMB8
PTGER3
R3HDM2
RAB5C
RALB
RAMAC
RBPMS
RECK
RFC3
RIPPLY3
RNF26
SAP18
SCNM1
SEC14L4
SHFL
SLC22A18AS
SMG9
SMUG1
SNRPB
SPAG8
SPG21
SPOUT1
SPRY1
STAMBPL1
STK16
STT3B
SUOX
TBC1D7
TCL1A
TEAD4
TEKT4
TEX12
TFAP2A
TFAP2D
TFAP4
TFG
THAP6
THRSP
TIAL1
TPRX1
TRAPPC2
TRAPPC2B
TRAPPC6A
TRIB3
TRIM26
TRIM55
TRIM63
TRIM68
TRIP13
TRIP6
TSEN15
TSG101
TSSK3
TSTD2
TXNDC17
UBASH3B
UBE2D4
UBE2Z
UBTD2
UBXN2B
UFM1
UFSP1
VEZF1
VGLL3
VPS26C
VPS28
WWOX
YIPF3
YOD1
ZDHHC24
ZFAND3
ZMYND12
ZMYND19
ZNF205-AS1
ZNF32
ZNF446
ZNF747
ZNF765
ZNRD2
82 interacting genes:
AK8
ARFIP2
ATP6V1D
BFSP2
BLOC1S6
BORCS6
C3orf62
CAGE1
CBY2
CCDC136
CCDC57
CCHCR1
CDR2
CENPP
CEP170P1
CEP44
CEP55
CEP57L1
CEP63
CEP70
DCTN2
DMD
DTNBP1
FAM161B
FGFR1OP2
GOLGA2
HGS
HOOK2
IFIT3
IFT20
INCA1
KDM1A
KIFC3
KRT1
KRT15
KRT18
KRT19
KRT3
KRT31
KRT38
KRT40
KXD1
LDOC1
LURAP1
MAD1L1
MAGEA6
MCM10
MCM3
MED4
MED7
MIPOL1
MTUS2
NDC80
NECAB2
NINL
NUP54
NUP62
ODAD1
PDE4DIP
PIBF1
PKN1
POLR3C
SPAG5
SSC5D
STX11
SYCE1
SYCE3
TEAD4
TFIP11
TFPT
TRAF1
TRIM23
TRIM27
TRIM54
TRIM69
TSG101
TXN2
USHBP1
VPS37C
VPS52
WASHC3
ZNF471
Entrez ID
388324
115106
HPRD ID
17150
16385
Ensembl ID
ENSG00000196388
ENSG00000152240
Uniprot IDs
Q0VD86
Q96CS2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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