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INCA1 and TRAPPC6A
Data Source:
BioGRID
(two hybrid)
INCA1
TRAPPC6A
Description
inhibitor of CDK, cyclin A1 interacting protein 1
trafficking protein particle complex subunit 6A
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Body
Golgi Membrane
Endoplasmic Reticulum
Cis-Golgi Network
Trans-Golgi Network
Cytosol
TRAPP Complex
Molecular Function
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Protein Binding
Cyclin Binding
Identical Protein Binding
Protein-containing Complex Binding
Protein Binding
Biological Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Apoptotic Signaling Pathway
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Regulation Of GTPase Activity
COPII Vesicle Coating
Melanosome Assembly
Pathways
COPII-mediated vesicle transport
RAB GEFs exchange GTP for GDP on RABs
Drugs
S-palmitoyl-L-cysteine
Diseases
GWAS
Intraocular pressure (
29235454
)
Obesity-related traits (
23251661
)
Alzheimer's disease (onset between ages 58 and 79) (
30979435
)
Alzheimer's disease or HDL levels (pleiotropy) (
30805717
)
Cerebrospinal fluid AB1-42 levels (
28247064
)
Interacting Genes
236 interacting genes:
ABI2
ACY3
AKAP8L
ANKRD28
ARMC7
ASPSCR1
ATG5
ATP6V0D2
ATPAF2
BAG3
BANF2
BOLA3
BPIFA1
C10orf55
C19orf54
C1orf35
C1orf50
C1orf56
C22orf39
CABP5
CCBE1
CCDC57
CCDC78
CCNA1
CDA
CDC23
CDK18
CDK2
CDK4
CDKN1A
CDKN2B
CDKN2D
CEP72
CHCHD2
CHCHD5
CHRD
CINP
CKS1B
CLIC3
CLK3
COL8A1
CPSF1
CSDC2
CSTF2
CTNNBIP1
CTTNBP2
CYSRT1
DAZAP2
DEF6
DMRT3
DMRTB1
DOK4
DPH7
DUSP13
EFEMP2
EMD
EPHB6
EXOSC8
FAAP20
FAIM
FEM1A
FGF16
FHL2
FMR1
FRS3
GEM
GEMIN2
GRB2
GRXCR1
GSTO2
GTF2H5
GTPBP3
GYS1
HAUS1
HCK
HDAC4
HEMK1
HENMT1
HNRNPF
HOMER3
HOXA1
HR
HSD17B14
HYI
IL36RN
ILF2
KCTD7
KCTD9
KIAA1217
KIR2DL4
KLHL26
KLHL42
KRT33B
KRT5
KRT75
KRTAP15-1
KRTAP19-1
KRTAP19-5
KRTAP19-6
KRTAP5-6
KRTAP6-2
KRTAP6-3
KRTAP9-3
LENG8
LGALS3
LHX3
LMNTD2
LMO2
LMO3
LSM3
LYPLA2
MAD2L2
MAGED4B
MAGOHB
MALSU1
MARF1
MARK1
MATN3
MBLAC1
METAP1
MPP1
MSRB1
MTMR9
NATD1
NCK2
NDUFAF3
NEDD9
NEIL2
NEK6
NFKBID
NHSL2
NME7
NMRK1
NPAS2
NTAQ1
NUBP2
NUDT16L1
NUDT22
OR6B1
OSGIN1
PADI3
PATE1
PCSK5
PCYT2
PDP1
PEF1
PFDN5
PHF1
PLA2G10
PLSCR3
POLR1C
POLR3C
POP5
POU4F2
PPP1R32
PRPH
PSMB2
PSMB8
PTGER3
R3HDM2
RAB5C
RALB
RAMAC
RBPMS
RECK
RFC3
RIPPLY3
RNF26
SAP18
SCNM1
SEC14L4
SHFL
SLC22A18AS
SMG9
SMUG1
SNRPB
SPAG8
SPG21
SPOUT1
SPRY1
STAMBPL1
STK16
STT3B
SUOX
TBC1D7
TCL1A
TEAD4
TEKT4
TEX12
TFAP2A
TFAP2D
TFAP4
TFG
THAP6
THRSP
TIAL1
TPRX1
TRAPPC2
TRAPPC2B
TRAPPC6A
TRIB3
TRIM26
TRIM55
TRIM63
TRIM68
TRIP13
TRIP6
TSEN15
TSG101
TSSK3
TSTD2
TXNDC17
UBASH3B
UBE2D4
UBE2Z
UBTD2
UBXN2B
UFM1
UFSP1
VEZF1
VGLL3
VPS26C
VPS28
WWOX
YIPF3
YOD1
ZDHHC24
ZFAND3
ZMYND12
ZMYND19
ZNF205-AS1
ZNF32
ZNF446
ZNF747
ZNF765
ZNRD2
47 interacting genes:
BAG4
CAVIN2
CD2BP2
CRYAB
CTDSP1
EFS
EYA2
FOXN1
GGA3
GINS3
GOLGA6A
GORASP2
HOXA1
HSPB8
IKZF3
INCA1
KANK4
KRTAP13-2
LHX4
MYOZ3
PAX6
PFDN5
PRR22
RAB3IP
RAD54B
REL
RUSC1
SCOC
SERTAD3
SF3B5
SMUG1
TAX1BP1
TEPSIN
TRAPPC10
TRAPPC12
TRAPPC2
TRAPPC2L
TRAPPC3
TRAPPC3L
TRAPPC6B
TRIM35
TTC23
UBAP2
YPEL3
ZFP90
ZMIZ2
ZNRD2
Entrez ID
388324
79090
HPRD ID
17150
14503
Ensembl ID
ENSG00000196388
ENSG00000007255
Uniprot IDs
Q0VD86
B7TZ90
O75865
PDB IDs
2C0J
2J3T
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Difference)
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Tagcloud (Intersection)
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