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BAG3 and ACD
Data Source:
BioGRID
(two hybrid)
BAG3
ACD
Description
BAG cochaperone 3
ACD shelterin complex subunit and telomerase recruitment factor
Image
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Aggresome
Z Disc
Neuron Projection
Chaperone Complex
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleoplasm
Telomerase Holoenzyme Complex
Nuclear Body
Shelterin Complex
Molecular Function
Adenyl-nucleotide Exchange Factor Activity
Protein Binding
Heat Shock Protein Binding
Protein-containing Complex Binding
Cadherin Binding
Dynein Intermediate Chain Binding
Chaperone Binding
Protein Binding
Telomeric DNA Binding
Protein-containing Complex Binding
DNA Polymerase Binding
Biological Process
Autophagosome Assembly
Protein Folding
Brain Development
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Spinal Cord Development
Cellular Response To Heat
Cellular Response To Unfolded Protein
Positive Regulation Of Protein Import Into Nucleus
Negative Regulation Of Apoptotic Process
Muscle Cell Cellular Homeostasis
Positive Regulation Of Protein Export From Nucleus
Regulation Of Catalytic Activity
Protein Stabilization
Chaperone-mediated Autophagy
Aggresome Assembly
Cellular Response To Mechanical Stimulus
Chaperone-mediated Protein Transport
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Protein Transport Along Microtubule
Regulation Of Cellular Response To Heat
Negative Regulation Of Protein Targeting To Mitochondrion
Positive Regulation Of Aggrephagy
Telomere Maintenance
Intracellular Protein Transport
Telomere Maintenance Via Telomerase
Telomere Capping
Protection From Non-homologous End Joining At Telomere
Telomere Assembly
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomerase Activity
Positive Regulation Of Single-stranded Telomeric DNA Binding
Protein Localization To Chromosome, Telomeric Region
Establishment Of Protein Localization To Telomere
Pathways
Regulation of HSF1-mediated heat shock response
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Diastolic blood pressure (
27841878
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Heart failure (
31919418
)
Idiopathic dilated cardiomyopathy (
21459883
)
Left ventricular ejection fraction (
32382064
32605384
)
Left ventricular end-systolic volume (
32382064
)
Parkinson's disease (
32201043
27182965
28892059
)
Parkinson's disease or first degree relation to individual with Parkinson's disease (
31701892
)
Hemoglobin levels (
32327693
)
Refractive error (
32231278
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
75 interacting genes:
ACD
ARRDC3
ATN1
ATXN7L2
BAIAP2L1
BCL2
CRYAB
CTDSP1
CYSRT1
CYSTM1
DAZAP2
DNM2
DTX3
DVL1
DVL2
DYNLT1
EGR4
EYA2
FAM168B
FAM189A2
FBXO7
FOXD4L1
GGN
GLIS3
HELT
HSPA1A
HSPA5
HSPA8
HSPB1
HSPB2
HSPB2-C11orf52
HSPB7
HSPB8
INCA1
LENG8
LITAF
LRRK1
LRRK2
MAGED1
MDFI
MRPL38
NIBAN3
NOTO
NR1H3
PDE9A
PDLIM7
PIH1D2
PLA2G10
PLCG1
PLEKHB1
POT1
PRDM6
PRKAR1B
PRR34
PTPN21
RUNX1
SF3B4
SHISA6
SIAH1
SPRY2
SRPK2
TBC1D3B
TBC1D3G
TINF2
TMEM174
TNK2
TP53BP2
TRIB3
TRIM27
TRIP6
TSC1
UNKL
VPS37B
WBP2
WNK1
63 interacting genes:
ACTB
ADPRH
AFAP1L2
AIPL1
ANKMY2
ANXA8L1
APOBEC3F
BAG3
CKB
CTTN
DBN1
DBNL
DCX
DPYSL3
EIF3G
EIF4B
ENO2
ENSA
FAM131B
FKBP6
GAPDH
HSP90AB1
IPO5
IVL
LASP1
LDHA
LGALSL
LLGL1
LRRC25
NCDN
NTAQ1
NUDC
NUDCD2
PAGE2
PDLIM2
PEX5
PFKP
PGM2
POT1
RBKS
RECQL4
RGS3
RPSA
SBDS
STIP1
STUB1
SULT1C2
TAGLN
TBC1D10A
TBCD
TINF2
TOMM34
TRIM15
TRIM16
TRIM55
TRIM63
TUBB2A
TUBB4B
USP7
XRCC6
YWHAE
ZFP36L1
ZNF790
Entrez ID
9531
65057
HPRD ID
04860
12417
Ensembl ID
ENSG00000151929
ENSG00000102977
Uniprot IDs
O95817
A0A590TQL1
Q96AP0
PDB IDs
2I46
5H65
5I2X
5I2Y
5UN7
5XYF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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