TRAPPC6A and KANK4

Data Source:
BioGRID (two hybrid)

		TRAPPC6A	KANK4
Description		trafficking protein particle complex subunit 6A	KN motif and ankyrin repeat domains 4
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	Cytoplasm Cytosol Cytoskeleton Microtubule Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly	Negative Regulation Of Actin Filament Polymerization
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS		Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)	Fuchs's corneal dystrophy ( 28358029) Regular attendance at a gym or sports club ( 29970889)
Interacting Genes		47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2	6 interacting genes: CSK CUL5 HAT1 HOMER3 MYLIP TRAPPC6A
Entrez ID		79090	163782
HPRD ID		14503	14109
Ensembl ID		ENSG00000007255	ENSG00000132854
Uniprot IDs		B7TZ90 O75865	B1ALP6 Q5T7N3
PDB IDs		2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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