TRAPPC6A and ZFP90

Data Source:
BioGRID (two hybrid)

		TRAPPC6A	ZFP90
Description		trafficking protein particle complex subunit 6A	ZFP90 zinc finger protein
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA Binding Positive Regulation Of Transcription, DNA-templated
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Generic Transcription Pathway
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS		Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)	Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) HIV-1 viral setpoint ( 22174851) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309) Systemic lupus erythematosus ( 27399966 28714469) Ulcerative colitis ( 28067908 23128233 21297633)
Interacting Genes		47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2	23 interacting genes: ABI2 ATPAF2 BOLA2 BOLA2B CCNC CPNE7 ENKD1 EXOSC5 GCC1 GLYCTK GTPBP3 HOXC8 LMO1 LONRF1 MALSU1 MLH1 NEK6 PRKAB2 RUNX1T1 TBC1D22B TDRKH TEKT4 TRAPPC6A
Entrez ID		79090	146198
HPRD ID		14503	18729
Ensembl ID		ENSG00000007255	ENSG00000184939
Uniprot IDs		B7TZ90 O75865	J3QKQ8 Q8TF47
PDB IDs		2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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