TRAPPC6A and SCOC

Data Source:
BioGRID (two hybrid)

		TRAPPC6A	SCOC
Description		trafficking protein particle complex subunit 6A	short coiled-coil protein
Image
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	Golgi Membrane Nucleoplasm Endosome Golgi Apparatus Trans-Golgi Network Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly	Positive Regulation Of Macroautophagy Regulation Of Protein Complex Stability
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Retrograde transport at the Trans-Golgi-Network
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS		Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)	Malaria ( 31844061) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2	16 interacting genes: ARL1 BFSP2 C21orf91 DDIT4L DOK5 FEZ1 FEZ2 ITSN1 KIFC3 KRT40 MAPK8 PSMC5 SCHIP1 SIKE1 TCF4 TRAPPC6A
Entrez ID		79090	60592
HPRD ID		14503	18027
Ensembl ID		ENSG00000007255	ENSG00000153130
Uniprot IDs		B7TZ90 O75865	Q9UIL1
PDB IDs		2C0J 2J3T	4BWD
Enriched GO Terms of Interacting Partners?
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