GDF9 and ILF3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GDF9	ILF3
Description		growth differentiation factor 9	interleukin enhancer binding factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Membrane Ribonucleoprotein Complex
	Molecular Function	Cytokine Activity Growth Factor Activity Type I Activin Receptor Binding	DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	Oocyte Growth Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth BMP Signaling Pathway SMAD Protein Signal Transduction Regulation Of Progesterone Secretion	Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Defense Response To Virus
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474)	Bipolar disorder ( 31043756) Chronotype ( 30696823) Height ( 25282103 25429064) Ischemic stroke ( 29531354) Obesity-related traits ( 23251661) Psoriasis ( 25903422 25574825 23143594) Psoriasis vulgaris ( 26626624) Rheumatoid arthritis ( 30423114) Stroke ( 29531354) Systemic lupus erythematosus ( 28714469)
Interacting Genes		45 interacting genes: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CDKN1A CDKN2C CRELD1 DLEU1 DNM2 FOXG1 FXYD6 GADD45G ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TDGF1 TK1 TRIB3 WASHC3	38 interacting genes: DHX9 DUX4 EIF2AK2 EP300 ERBB2 ERG ESR1 FUS GDF9 HNRNPH2 IL7R KRTAP4-12 LNX1 MAGEA11 MDFI NDRG1 PLSCR1 PPP1R12A PRMT1 PRMT5 PTEN RBM5 RBPMS RNF113A SF1 SF3B4 SMN1 SNRPC TRIM55 TRIM63 TRIP6 UBC UBE2D2 VPS37C XAB2 XPO5 ZNF346 ZNF830
Entrez ID		2661	3609
HPRD ID		03560	04420
Ensembl ID		ENSG00000164404	ENSG00000129351
Uniprot IDs		B4DXG3 O60383	A0A024R7C7 Q12906
PDB IDs			2L33 3P1X
Enriched GO Terms of Interacting Partners?
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