GDF9 and PAFAH1B3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GDF9	PAFAH1B3
Description		growth differentiation factor 9	platelet activating factor acetylhydrolase 1b catalytic subunit 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Cytoplasm Cytosol 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Membrane
	Molecular Function	Cytokine Activity Growth Factor Activity Type I Activin Receptor Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity
	Biological Process	Oocyte Growth Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth BMP Signaling Pathway SMAD Protein Signal Transduction Regulation Of Progesterone Secretion	Lipid Metabolic Process Spermatogenesis Nervous System Development Brain Development Lipid Catabolic Process
Pathways			COPI-independent Golgi-to-ER retrograde traffic
Drugs			(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Diseases
GWAS		Asthma ( 31619474)
Interacting Genes		45 interacting genes: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CDKN1A CDKN2C CRELD1 DLEU1 DNM2 FOXG1 FXYD6 GADD45G ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TDGF1 TK1 TRIB3 WASHC3	36 interacting genes: BRD7 CCDC90B CHMP7 COPS6 CRMP1 DDX24 ECH1 EEF1A1 ERG28 GAPDH GBP2 GDF9 HSPH1 IGSF21 LNX1 LRIF1 MED31 MEI4 NIF3L1 PAFAH1B1 PAFAH1B2 PICK1 PLEKHM1 RBM48 SDCBP2 SETDB1 SUMO4 TERF1 TERF2IP TLE1 TP53 TUBB2A UNC119 XRCC6 ZBTB16 ZHX1
Entrez ID		2661	5050
HPRD ID		03560	04354
Ensembl ID		ENSG00000164404	ENSG00000079462
Uniprot IDs		B4DXG3 O60383	A0A024R0L6 Q15102
PDB IDs
Enriched GO Terms of Interacting Partners?
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