ARF3 and GGA3

Data Source:
BioGRID (two hybrid, two hybrid)

		ARF3	GGA3
Description		ADP ribosylation factor 3	golgi associated, gamma adaptin ear containing, ARF binding protein 3
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Lysosome Golgi Apparatus Trans-Golgi Network Endosome Membrane Early Endosome Membrane Protein-containing Complex Recycling Endosome Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein Binding Small GTPase Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle-mediated Transport	Protein Targeting To Lysosome Intracellular Protein Transport Regulation Of Protein Stability Protein Destabilization Endocytic Recycling Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Amyloid-beta Formation
Pathways		Synthesis of PIPs at the Golgi membrane COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	TBC/RABGAPs MET receptor recycling Amyloid fiber formation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Heel bone mineral density ( 30598549)
Interacting Genes		16 interacting genes: APBA1 APBA2 APBA3 ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 GORAB KIF23 LNX1 PICK1 SCYL1 SLC2A4 SUMO2	38 interacting genes: ADRA2A ADRA2B AFTPH AP1S2 ARAP3 ARF1 ARF3 CDKN2A CLINT1 CLTC CYTH2 DAZAP2 EGFR GGA1 GGA2 IGF2R LITAF LRP10 M6PR P4HA3 PACS1 PLEKHB2 RABEP1 RNF11 RNF214 RPS27A STAB1 SYNRG TBC1D3 TOLLIP TRAPPC6A TRIM23 TSG101 UBC UPRT VPS11 VPS18 ZNF497
Entrez ID		377	23163
HPRD ID		00056	10443
Ensembl ID		ENSG00000134287	ENSG00000125447
Uniprot IDs		A0A024R0Y6 P61204	A8K6M0 B7Z456 Q9NZ52
PDB IDs		6II6	1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8
Enriched GO Terms of Interacting Partners?
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