ARF3 and KIF23

Data Source:
HPRD (in vitro, two hybrid)

		ARF3	KIF23
Description		ADP ribosylation factor 3	kinesin family member 23
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Nucleoplasm Centrosome Spindle Cytosol Kinesin Complex Microtubule Focal Adhesion Midbody Mitotic Spindle Flemming Body Centralspindlin Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle-mediated Transport	Mitotic Spindle Elongation Mitotic Cytokinesis Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly
Pathways		Synthesis of PIPs at the Golgi membrane COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Heel bone mineral density ( 30598549)	Mean reticulocyte volume ( 32888494) Rheumatoid arthritis (ACPA-positive) ( 24532676)
Interacting Genes		16 interacting genes: APBA1 APBA2 APBA3 ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 GORAB KIF23 LNX1 PICK1 SCYL1 SLC2A4 SUMO2	13 interacting genes: ACTA1 ARF3 CLK1 LATS2 PLK1 PPP1CB RACGAP1 RBM34 SUMO2 USP8 YWHAB YWHAG YWHAQ
Entrez ID		377	9493
HPRD ID		00056	05455
Ensembl ID		ENSG00000134287	ENSG00000137807
Uniprot IDs		A0A024R0Y6 P61204	Q02241
PDB IDs		6II6	3VHX
Enriched GO Terms of Interacting Partners?
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