GGA3 and LRP10

Data Source:
BioGRID (pull down)

		GGA3	LRP10
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 3	LDL receptor related protein 10
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Golgi Apparatus Trans-Golgi Network Endosome Membrane Early Endosome Membrane Protein-containing Complex Recycling Endosome Membrane	Clathrin-coated Pit Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Small GTPase Binding Ubiquitin Binding Protein-containing Complex Binding	Low-density Lipoprotein Particle Receptor Activity Protein Binding
	Biological Process	Protein Targeting To Lysosome Intracellular Protein Transport Regulation Of Protein Stability Protein Destabilization Endocytic Recycling Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Amyloid-beta Formation	Lipid Metabolic Process Lipid Transport Endocytosis Inner Ear Development
Pathways		TBC/RABGAPs MET receptor recycling Amyloid fiber formation	Retinoid metabolism and transport
Drugs
Diseases
GWAS			Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Neutrophil count ( 32888494)
Interacting Genes		38 interacting genes: ADRA2A ADRA2B AFTPH AP1S2 ARAP3 ARF1 ARF3 CDKN2A CLINT1 CLTC CYTH2 DAZAP2 EGFR GGA1 GGA2 IGF2R LITAF LRP10 M6PR P4HA3 PACS1 PLEKHB2 RABEP1 RNF11 RNF214 RPS27A STAB1 SYNRG TBC1D3 TOLLIP TRAPPC6A TRIM23 TSG101 UBC UPRT VPS11 VPS18 ZNF497	23 interacting genes: C16orf92 CISD2 EBP FAM209A GGA3 GJB5 GOLM2 GORAB HTRA1 LMNA MFSD14B MGST3 MRPS18B NOTO PDCD1LG2 PLEKHO1 SLC10A1 SLC14A2 SMIM1 ST6GALNAC6 TMEM179B TMEM237 TMEM243
Entrez ID		23163	26020
HPRD ID		10443	14311
Ensembl ID		ENSG00000125447	ENSG00000197324
Uniprot IDs		A8K6M0 B7Z456 Q9NZ52	Q7Z4F1
PDB IDs		1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8
Enriched GO Terms of Interacting Partners?
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