ARF3 and APBA1

Data Source:
BioGRID (two hybrid)

		ARF3	APBA1
Description		ADP ribosylation factor 3	amyloid beta precursor protein binding family A member 1
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Dendritic Spine Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Amyloid-beta Binding Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle-mediated Transport	In Utero Embryonic Development Intracellular Protein Transport Cell Adhesion Chemical Synaptic Transmission Neurotransmitter Secretion Nervous System Development Locomotory Behavior Axo-dendritic Transport Regulation Of Gene Expression Glutamate Secretion Gamma-aminobutyric Acid Secretion Multicellular Organism Growth Protein-containing Complex Assembly Regulation Of Synaptic Vesicle Exocytosis
Pathways		Synthesis of PIPs at the Golgi membrane COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Heel bone mineral density ( 30598549)	Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Refractive error ( 32231278)
Interacting Genes		16 interacting genes: APBA1 APBA2 APBA3 ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 GORAB KIF23 LNX1 PICK1 SCYL1 SLC2A4 SUMO2	17 interacting genes: APP ARF3 ARF4 CACNA1B CASK CCS CNTNAP3 CNTNAP4 HTR2C KCNJ12 KIF17 LIN7B NOTCH1 NRXN1 PSEN1 STX1A STXBP1
Entrez ID		377	320
HPRD ID		00056	03879
Ensembl ID		ENSG00000134287	ENSG00000107282
Uniprot IDs		A0A024R0Y6 P61204	Q02410
PDB IDs		6II6	1AQC 1U37 1U38 1U39 1U3B 1X11 1X45 1Y7N
Enriched GO Terms of Interacting Partners?
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