GGA3 and ARF3

Data Source:
BioGRID (two hybrid, two hybrid)

		GGA3	ARF3
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 3	ADP ribosylation factor 3
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GO Annotations	Cellular Component	Lysosome Golgi Apparatus Trans-Golgi Network Endosome Membrane Early Endosome Membrane Protein-containing Complex Recycling Endosome Membrane	Golgi Membrane Cytoplasm Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding Ubiquitin Binding Protein-containing Complex Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Protein Targeting To Lysosome Intracellular Protein Transport Regulation Of Protein Stability Protein Destabilization Endocytic Recycling Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Amyloid-beta Formation	Phosphatidylinositol Biosynthetic Process Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle-mediated Transport
Pathways		TBC/RABGAPs MET receptor recycling Amyloid fiber formation	Synthesis of PIPs at the Golgi membrane COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Heel bone mineral density ( 30598549)
Interacting Genes		38 interacting genes: ADRA2A ADRA2B AFTPH AP1S2 ARAP3 ARF1 ARF3 CDKN2A CLINT1 CLTC CYTH2 DAZAP2 EGFR GGA1 GGA2 IGF2R LITAF LRP10 M6PR P4HA3 PACS1 PLEKHB2 RABEP1 RNF11 RNF214 RPS27A STAB1 SYNRG TBC1D3 TOLLIP TRAPPC6A TRIM23 TSG101 UBC UPRT VPS11 VPS18 ZNF497	16 interacting genes: APBA1 APBA2 APBA3 ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 GORAB KIF23 LNX1 PICK1 SCYL1 SLC2A4 SUMO2
Entrez ID		23163	377
HPRD ID		10443	00056
Ensembl ID		ENSG00000125447	ENSG00000134287
Uniprot IDs		A8K6M0 B7Z456 Q9NZ52	A0A024R0Y6 P61204
PDB IDs		1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8	6II6
Enriched GO Terms of Interacting Partners?
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