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ITGA5 and ANGPT2
Data Source:
BioGRID
(pull down, affinity chromatography technology)
ITGA5
ANGPT2
Description
integrin subunit alpha 5
angiopoietin 2
Image
GO Annotations
Cellular Component
Ruffle
Endoplasmic Reticulum
Golgi Apparatus
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Cytoplasmic Vesicle
Ruffle Membrane
Integrin Alpha5-beta1 Complex
Synapse
Alphav-beta3 Integrin-vitronectin Complex
Extracellular Region
Extracellular Space
Nucleus
Plasma Membrane
Cell Projection
Collagen-containing Extracellular Matrix
Molecular Function
Virus Receptor Activity
Epidermal Growth Factor Receptor Binding
Platelet-derived Growth Factor Receptor Binding
Integrin Binding
Protein Binding
Vascular Endothelial Growth Factor Receptor 2 Binding
Metal Ion Binding
Signaling Receptor Binding
Protein Binding
Receptor Tyrosine Kinase Binding
Metal Ion Binding
Biological Process
Angiogenesis
Cell-substrate Junction Assembly
Cell Adhesion
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Leukocyte Cell-cell Adhesion
Integrin-mediated Signaling Pathway
Female Pregnancy
Memory
Positive Regulation Of Cell-substrate Adhesion
CD40 Signaling Pathway
Extracellular Matrix Organization
Positive Regulation Of Cell Migration
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell-substrate Adhesion
Cell Adhesion Mediated By Integrin
Cell-cell Adhesion Mediated By Integrin
Heterotypic Cell-cell Adhesion
Wound Healing, Spreading Of Epidermal Cells
Endodermal Cell Differentiation
Viral Entry Into Host Cell
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Leukocyte Migration
Positive Regulation Of Sprouting Angiogenesis
Negative Regulation Of Anoikis
Angiogenesis
Response To Hypoxia
Signal Transduction
Germ Cell Development
Response To Radiation
Response To Mechanical Stimulus
Response To Glucose
Gene Expression
Negative Regulation Of Cell-substrate Adhesion
Response To Organic Cyclic Compound
Response To Activity
Negative Regulation Of Angiogenesis
Animal Organ Regeneration
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Angiogenesis
Tie Signaling Pathway
Leukocyte Migration
Negative Regulation Of Positive Chemotaxis
Maternal Process Involved In Female Pregnancy
Cellular Response To Growth Factor Stimulus
Glomerulus Vasculature Development
Pathways
Elastic fibre formation
Fibronectin matrix formation
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Integrin cell surface interactions
Signal transduction by L1
RUNX2 regulates genes involved in cell migration
Tie2 Signaling
Drugs
Resveratrol
Faricimab
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Alcoholic chronic pancreatitis (
28754779
)
Blood protein levels (
30072576
)
Dental caries (decayed and filled deciduous teeth) (
31533690
)
Intraocular pressure (
29617998
29785010
30054594
)
Metabolite levels (
23823483
)
Response to cytidine analogues (gemcitabine) (
24483146
)
Interacting Genes
31 interacting genes:
ANGPT1
ANGPT2
ANGPTL3
ARHGAP5
AUP1
CD9
CLK1
COL18A1
COL1A1
EGFR
ERBB2
FGFR2
FLT4
FN1
GIPC1
GPR182
GRK6
ITGB1
ITGB3
ITGB5
L1CAM
LGALS3BP
NISCH
PECAM1
RABIF
SHARPIN
SPP1
STAMBP
TNC
UBAP1
VCL
6 interacting genes:
ANGPT1
ANXA7
CDKN1A
CSNK2B
ITGA5
TEK
Entrez ID
3678
285
HPRD ID
00627
03563
Ensembl ID
ENSG00000161638
ENSG00000091879
Uniprot IDs
B2R627
P08648
O15123
PDB IDs
3VI3
3VI4
4WJK
4WK0
4WK2
4WK4
1Z3S
1Z3U
2GY7
4JZC
4ZFG
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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