Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
ITGA5 and GIPC1
Data Source:
HPRD
(in vitro, two hybrid)
ITGA5
GIPC1
Description
integrin subunit alpha 5
GIPC PDZ domain containing family member 1
Image
No pdb structure
GO Annotations
Cellular Component
Ruffle
Endoplasmic Reticulum
Golgi Apparatus
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Cytoplasmic Vesicle
Ruffle Membrane
Integrin Alpha5-beta1 Complex
Synapse
Alphav-beta3 Integrin-vitronectin Complex
Cytoplasm
Cytosol
Brush Border
Cell Cortex
Synaptic Vesicle
Vesicle Membrane
Membrane
Endocytic Vesicle
Cytoplasmic Vesicle
Dendritic Spine
Dendritic Shaft
Extracellular Exosome
Schaffer Collateral - CA1 Synapse
Glutamatergic Synapse
Molecular Function
Virus Receptor Activity
Epidermal Growth Factor Receptor Binding
Platelet-derived Growth Factor Receptor Binding
Integrin Binding
Protein Binding
Vascular Endothelial Growth Factor Receptor 2 Binding
Metal Ion Binding
Actin Binding
Signaling Receptor Binding
Protein Binding
Myosin Binding
PDZ Domain Binding
Identical Protein Binding
Cadherin Binding
Biological Process
Angiogenesis
Cell-substrate Junction Assembly
Cell Adhesion
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Leukocyte Cell-cell Adhesion
Integrin-mediated Signaling Pathway
Female Pregnancy
Memory
Positive Regulation Of Cell-substrate Adhesion
CD40 Signaling Pathway
Extracellular Matrix Organization
Positive Regulation Of Cell Migration
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell-substrate Adhesion
Cell Adhesion Mediated By Integrin
Cell-cell Adhesion Mediated By Integrin
Heterotypic Cell-cell Adhesion
Wound Healing, Spreading Of Epidermal Cells
Endodermal Cell Differentiation
Viral Entry Into Host Cell
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Leukocyte Migration
Positive Regulation Of Sprouting Angiogenesis
Negative Regulation Of Anoikis
Protein Targeting
G Protein-coupled Receptor Signaling Pathway
Chemical Synaptic Transmission
Glutamate Secretion
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Protein Stability
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cytokinesis
Endothelial Cell Migration
Positive Regulation Of Melanin Biosynthetic Process
Regulation Of Synaptic Plasticity
Cellular Response To Interleukin-7
Regulation Of Synaptic Vesicle Exocytosis
Pathways
Elastic fibre formation
Fibronectin matrix formation
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Integrin cell surface interactions
Signal transduction by L1
RUNX2 regulates genes involved in cell migration
Drugs
Resveratrol
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Kidney stones (
31729369
)
Interacting Genes
31 interacting genes:
ANGPT1
ANGPT2
ANGPTL3
ARHGAP5
AUP1
CD9
CLK1
COL18A1
COL1A1
EGFR
ERBB2
FGFR2
FLT4
FN1
GIPC1
GPR182
GRK6
ITGB1
ITGB3
ITGB5
L1CAM
LGALS3BP
NISCH
PECAM1
RABIF
SHARPIN
SPP1
STAMBP
TNC
UBAP1
VCL
36 interacting genes:
ACTN1
ADRB1
CARD10
CD93
DDIT3
DRD2
DRD3
FZD3
GSK3B
IGF1R
ITGA5
ITGA6
KIF1B
LHCGR
LPAR1
LPAR2
LRP1
LRP2
LRP8
MYO6
NRP1
NTRK1
NTRK2
PLEKHA2
RGS1
RGS19
SDC4
SEMA4B
SEMA4C
SH3BP4
SLC2A1
TGFBR3
TPBG
TYRP1
ZFPM1
ZNF408
Entrez ID
3678
10755
HPRD ID
00627
05462
Ensembl ID
ENSG00000161638
ENSG00000123159
Uniprot IDs
B2R627
P08648
A0A024R7I0
A0A024R7I1
A8K2I7
O14908
PDB IDs
3VI3
3VI4
4WJK
4WK0
4WK2
4WK4
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?