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AQP1 and MKRN3
Data Source:
BioGRID
(two hybrid)
AQP1
MKRN3
Description
aquaporin 1 (Colton blood group)
makorin ring finger protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Ribonucleoprotein Complex
Molecular Function
Intracellular CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Protein Binding
Identical Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Renal Water Homeostasis
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Cellular Water Homeostasis
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Odontogenesis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Defense Response To Gram-negative Bacterium
Multicellular Organismal Water Homeostasis
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Protein Polyubiquitination
Protein Ubiquitination
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Drugs
Acetazolamide
B-nonylglucoside
Mersalyl
Diseases
GWAS
Fractures (
30598549
)
Heel bone mineral density (
30598549
28869591
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Height (
31562340
)
Menarche (age at onset) (
25231870
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Interacting Genes
134 interacting genes:
ADAMTSL4
AMOT
AQP6
BCL2L13
BEGAIN
BHLHB9
BLZF1
BMF
CCDC136
CCDC57
CCDC85B
CCNDBP1
CD79A
CDR2
CEP44
CLDN5
COMP
CPLX4
CREB3
CRTAC1
CSRNP1
CYSRT1
EFEMP2
EPHB2
ESM1
EVI2B
FAM161A
FAM209A
FNDC9
FOS
FSD2
GET1
GJB5
GLI1
GOLGA2
GPR37L1
GPX8
IFT20
IGFBP6
IHO1
IKZF2
IKZF3
IL21R
KCNK5
KCTD17
KCTD9
KHDRBS3
KIAA1958
KLHL26
KRT31
KRT33B
KRT37
KRT40
KRTAP1-1
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-4
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE1A
LDLRAD1
LDOC1
LIME1
LMNA
LPXN
LRRC59
MDFI
MGST3
MID2
MIF4GD
MKRN3
MRM1
MTUS2
MUC1
MYF5
NBPF19
NBPF22P
NBPF6
NOTCH2NLA
NUTM1
PGPEP1
PICK1
PLA2G10
PLSCR2
PPARA
PRDM14
PRDM6
RBAK
REL
RGS17
RGS20
RIMBP3
RNF122
SAR1A
SIAH1
SIVA1
SLC15A2
SLC39A2
SPDYA
SPRED1
SPRED2
SPRY2
SPRY3
SPRYD7
SSMEM1
TCF4
TMEM237
TMEM38B
TMEM45B
TMEM80
TMPRSS2
TNK2
TNS2
TRAF1
TRAF2
TRIM23
TRIM37
TRIM41
TRIM42
TRIM7
TRIP6
TSC1
ZBTB39
ZIM2
ZNF16
ZNF398
ZNF792
178 interacting genes:
ACOT11
ADAMTSL4
ADRA2C
ANKRD11
ANTKMT
APEX2
AQP1
ARID5A
ARMC5
AVPI1
BATF2
BCL2L11
BEX2
BLZF1
BPIFA1
C10orf82
C21orf58
CCDC120
CCDC185
CCDC187
CCDC33
CDCA4
CEP70
CERCAM
CRACR2A
CYSRT1
DDIT4L
ECM1
ECSIT
EFEMP1
ENKD1
ERCC1
FAM110A
FAM124B
FAM214B
FARS2
GADD45GIP1
GATA1
GEM
GOLGA6A
GRAP2
HCK
HGS
HOXA1
HOXD12
HSF2BP
HSF4
IGF1
IKZF3
INO80B
KANK2
KIF1A
KIFC3
KLF1
KLHL38
KRT34
KRT75
KRT86
KRTAP19-2
KRTAP19-6
KRTAP19-7
KRTAP21-2
KRTAP6-2
KRTAP7-1
KRTAP8-1
LAGE3
LASP1
LRSAM1
MAGED1
MBD3
MCCD1
MDM2
MDM4
MEOX1
MEOX2
MGAT5B
MIF4GD
MNAT1
MORN3
MRPL38
MRPS6
MYOZ2
NABP1
NDE1
NDUFB7
NKAPD1
NME4
ODAD4
ODF3B
PEX10
PEX5
PKN1
POLR1C
POMC
PRKAA2
PRPF31
PRR22
PRR35
PSMA1
PSMB1
PTH1R
PTK6
RASD1
RBM41
RBPMS
RBPMS2
RIBC1
RNF166
RNF32
RNF7
RSPO4
RTP5
SCNM1
SF1
SFN
SLPI
SMARCD1
SMYD3
SNRPC
SORBS3
SPATA8
STH
STMN3
STN1
SYNGAP1
TADA2A
TASOR2
TCEA2
TCHP
TCL1B
TENT5B
TFAP2A
TFIP11
TLE5
TPRX1
TRAF2
TRIM23
TRIM31
TRIM34
TRIM5
TRIM65
TRIM8
TSG101
TSGA10IP
TSPAN4
TTC23
TXNDC11
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2I
UBE2K
UBE2L3
UBE2N
UBE2U
UBE2V1
UBE2V2
UBE2W
UQCC2
USHBP1
VPS9D1
WDR25
WWOX
YPEL3
ZBTB42
ZFC3H1
ZFP57
ZIM2
ZNF34
ZNF414
ZNF587
ZNF688
ZNF835
Entrez ID
358
7681
HPRD ID
00140
04836
Ensembl ID
ENSG00000240583
ENSG00000179455
Uniprot IDs
A0A024RA31
P29972
Q13064
PDB IDs
1FQY
1H6I
1IH5
4CSK
6POJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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