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AQP1 and KRTAP1-1
Data Source:
BioGRID
(two hybrid)
AQP1
KRTAP1-1
Description
aquaporin 1 (Colton blood group)
keratin associated protein 1-1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Cytosol
Keratin Filament
Molecular Function
Intracellular CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Protein Binding
Biological Process
Renal Water Homeostasis
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Cellular Water Homeostasis
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Odontogenesis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Defense Response To Gram-negative Bacterium
Multicellular Organismal Water Homeostasis
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Biological_process
Keratinization
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Keratinization
Drugs
Acetazolamide
B-nonylglucoside
Mersalyl
Diseases
GWAS
Fractures (
30598549
)
Heel bone mineral density (
30598549
28869591
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Interacting Genes
134 interacting genes:
ADAMTSL4
AMOT
AQP6
BCL2L13
BEGAIN
BHLHB9
BLZF1
BMF
CCDC136
CCDC57
CCDC85B
CCNDBP1
CD79A
CDR2
CEP44
CLDN5
COMP
CPLX4
CREB3
CRTAC1
CSRNP1
CYSRT1
EFEMP2
EPHB2
ESM1
EVI2B
FAM161A
FAM209A
FNDC9
FOS
FSD2
GET1
GJB5
GLI1
GOLGA2
GPR37L1
GPX8
IFT20
IGFBP6
IHO1
IKZF2
IKZF3
IL21R
KCNK5
KCTD17
KCTD9
KHDRBS3
KIAA1958
KLHL26
KRT31
KRT33B
KRT37
KRT40
KRTAP1-1
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-4
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE1A
LDLRAD1
LDOC1
LIME1
LMNA
LPXN
LRRC59
MDFI
MGST3
MID2
MIF4GD
MKRN3
MRM1
MTUS2
MUC1
MYF5
NBPF19
NBPF22P
NBPF6
NOTCH2NLA
NUTM1
PGPEP1
PICK1
PLA2G10
PLSCR2
PPARA
PRDM14
PRDM6
RBAK
REL
RGS17
RGS20
RIMBP3
RNF122
SAR1A
SIAH1
SIVA1
SLC15A2
SLC39A2
SPDYA
SPRED1
SPRED2
SPRY2
SPRY3
SPRYD7
SSMEM1
TCF4
TMEM237
TMEM38B
TMEM45B
TMEM80
TMPRSS2
TNK2
TNS2
TRAF1
TRAF2
TRIM23
TRIM37
TRIM41
TRIM42
TRIM7
TRIP6
TSC1
ZBTB39
ZIM2
ZNF16
ZNF398
ZNF792
189 interacting genes:
ADAM12
ADAMTSL3
ADAMTSL4
AGXT
AKR7A3
ALDH3B1
ALPP
AQP1
ASPSCR1
ATG9A
BCAM
C10orf62
C11orf87
C19orf38
CAMK2B
CATIP
CATSPER1
CD300LG
CERK
CHIC2
CHRD
CHRNG
CLDN2
CNNM3
CRY2
CSF1
CST2
CTRC
CTSZ
CYHR1
CYSLTR2
CYSRT1
DHRS1
DMRT3
DOCK2
EFNA3
EMC7
FAM221A
FAM71C
FAM76B
FAM90A1
FARS2
FEZF1
FKBP1B
FOXD4L3
FRS3
FZD10
GLP1R
GNE
GRN
GSTP1
GUCD1
HCK
HEY2
HOXA1
HOXB5
HOXB9
HOXC8
HPCAL1
HSBP1
HYAL2
IFITM2
IGSF8
IL16
INS
ITGB4
ITGB5
JOSD1
KLHL38
KLK8
KRT20
KRTAP10-1
KRTAP10-11
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP12-3
KRTAP13-2
KRTAP2-3
KRTAP2-4
KRTAP26-1
KRTAP4-12
KRTAP4-5
KRTAP5-11
KRTAP5-4
KRTAP5-6
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1E
LCE1F
LCE2B
LCE2C
LCE2D
LCE3B
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LNX1
LRFN4
LRRN4
MAGOHB
MAPKBP1
MELTF
MGAT5B
MRGBP
MRPL23
MT1B
MXD3
MXI1
MYOM1
NECTIN2
NECTIN3
NMU
NPDC1
NR1D2
NTM
NUBP2
OLIG3
OR14I1
OTX1
P2RX4
P2RY6
PCSK5
PDE9A
PGAP6
PHLDA1
PRKAB2
PRKAG1
PRPF31
PSMA1
PVR
QPRT
R3HDM2
REM2
RNF111
RPS19BP1
RPS28
RPUSD3
RTN4RL1
SCARF1
SCNM1
SDC3
SEMA3B
SHFL
SLC23A1
SLC43A2
SLC6A20
SLC7A11
SLIT1
SMARCE1
SMCP
SMOC1
SNAI1
SNX18
SPACA9
SPRY1
STK16
TCEANC
TFAP2D
TGFB1
TNP2
TSFM
VASN
VGLL3
VSTM4
WNT11
ZBTB48
ZBTB9
ZDHHC1
ZNF124
ZNF330
ZNF408
ZNF439
ZNF440
ZNF446
ZNF491
ZNF497
ZNF524
ZNF581
ZNF587
ZNF648
ZNF669
ZNF696
ZNF786
ZNF837
Entrez ID
358
81851
HPRD ID
00140
12304
Ensembl ID
ENSG00000240583
ENSG00000188581
Uniprot IDs
A0A024RA31
P29972
Q07627
PDB IDs
1FQY
1H6I
1IH5
4CSK
6POJ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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