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AQP1 and KRTAP6-2
Data Source:
BioGRID
(two hybrid)
AQP1
KRTAP6-2
Description
aquaporin 1 (Colton blood group)
keratin associated protein 6-2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Cytosol
Intermediate Filament
Molecular Function
Intracellular CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Protein Binding
Identical Protein Binding
Biological Process
Renal Water Homeostasis
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Cellular Water Homeostasis
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Odontogenesis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Defense Response To Gram-negative Bacterium
Multicellular Organismal Water Homeostasis
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Keratinization
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Keratinization
Drugs
Acetazolamide
B-nonylglucoside
Mersalyl
Diseases
GWAS
Fractures (
30598549
)
Heel bone mineral density (
30598549
28869591
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Interacting Genes
134 interacting genes:
ADAMTSL4
AMOT
AQP6
BCL2L13
BEGAIN
BHLHB9
BLZF1
BMF
CCDC136
CCDC57
CCDC85B
CCNDBP1
CD79A
CDR2
CEP44
CLDN5
COMP
CPLX4
CREB3
CRTAC1
CSRNP1
CYSRT1
EFEMP2
EPHB2
ESM1
EVI2B
FAM161A
FAM209A
FNDC9
FOS
FSD2
GET1
GJB5
GLI1
GOLGA2
GPR37L1
GPX8
IFT20
IGFBP6
IHO1
IKZF2
IKZF3
IL21R
KCNK5
KCTD17
KCTD9
KHDRBS3
KIAA1958
KLHL26
KRT31
KRT33B
KRT37
KRT40
KRTAP1-1
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-4
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE1A
LDLRAD1
LDOC1
LIME1
LMNA
LPXN
LRRC59
MDFI
MGST3
MID2
MIF4GD
MKRN3
MRM1
MTUS2
MUC1
MYF5
NBPF19
NBPF22P
NBPF6
NOTCH2NLA
NUTM1
PGPEP1
PICK1
PLA2G10
PLSCR2
PPARA
PRDM14
PRDM6
RBAK
REL
RGS17
RGS20
RIMBP3
RNF122
SAR1A
SIAH1
SIVA1
SLC15A2
SLC39A2
SPDYA
SPRED1
SPRED2
SPRY2
SPRY3
SPRYD7
SSMEM1
TCF4
TMEM237
TMEM38B
TMEM45B
TMEM80
TMPRSS2
TNK2
TNS2
TRAF1
TRAF2
TRIM23
TRIM37
TRIM41
TRIM42
TRIM7
TRIP6
TSC1
ZBTB39
ZIM2
ZNF16
ZNF398
ZNF792
185 interacting genes:
ADAM12
ADAMTSL4
ANAPC11
ANKS1A
ANXA11
APOBEC1
AQP1
ARID5A
ATG9A
ATN1
ATPAF2
BEX2
BHLHE40
C10orf55
C1orf94
C20orf85
C6orf15
CAMK2A
CAMK2B
CASC3
CATSPER1
CCDC120
CCDC17
CCDC28A-AS1
CCER1
CCNK
CELF5
CERCAM
CERK
CFP
CHIC2
COL8A1
CREB5
CTRC
CYSRT1
DAZAP2
DHRS1
DMRT3
ENKD1
ESR2
FAAP20
FAM166B
FAM168A
FAM214B
FAM83A
FOXD2
FOXD4L1
FOXD4L3
FOXP3
FRS3
GALT
GATA3
GCM2
GLIS2
GLYCTK
GNE
GPS2
GRINA
GRN
GSTP1
HAPLN2
HELT
HEY1
HEY2
HEYL
HHEX
HOXA1
HOXB9
HOXC8
HOXC9
HSF4
HYAL2
IGFN1
INCA1
INO80B
ITGB4
KLHL38
KPRP
KRT83
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP15-1
KRTAP19-5
KRTAP26-1
KRTAP3-3
KRTAP4-11
KRTAP4-12
KRTAP6-1
KRTAP6-3
LASP1
LCE2B
LCE2D
LCE5A
LETM1
LGALS9C
LRFN4
LRRC41
LYVE1
MEIS2
MGAT5B
MKRN3
NAF1
NDUFA9
NEU4
NFKBID
NID2
NPBWR2
NR1D2
NSD1
OLIG3
OTX1
PATL1
PATZ1
PAX3
PDP1
PHLDA1
PITX1
PKD2
PLEKHN1
PLSCR4
POGZ
POU5F2
PPP1R32
PRR13
PRR3
PRR30
PRR35
RASD1
RBFOX2
RBPMS2
RERE
RHOXF2
RNF38
ROR2
RTP5
RUNX1T1
RUSC1
SAMD7
SHARPIN
SIAH3
SMAP2
SMARCC1
SMN1
SMN2
SMUG1
SNRPB
SNRPC
SPAG8
SPATA8
TBX6
TCF7L2
TEKT3
TEKT4
TEKT5
TENT5B
TENT5D
TEPSIN
TEX37
TFAP2D
TLE5
TLX2
TLX3
TNIP1
TOLLIP
TPRX1
TRIP13
TSGA10IP
TSPAN4
TSPYL6
VAC14
VENTX
VGLL3
VPS37C
YPEL3
ZBTB32
ZC3H10
ZIC1
ZNF414
ZNF503
ZNF581
ZNF683
ZNF843
Entrez ID
358
337967
HPRD ID
00140
11219
Ensembl ID
ENSG00000240583
ENSG00000186930
Uniprot IDs
A0A024RA31
P29972
Q3LI66
PDB IDs
1FQY
1H6I
1IH5
4CSK
6POJ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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