PADI6 and KLHL2

		PADI6	KLHL2
Description		peptidyl arginine deiminase 6	kelch like family member 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Intermediate Filament Cytoskeleton	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein-arginine Deiminase Activity Calcium Ion Binding Protein Binding	Actin Binding Protein Binding Identical Protein Binding
	Biological Process	Cytoskeleton Organization Cytoplasm Organization Histone Citrullination Regulation Of Translation By Machinery Localization	Protein Ubiquitination Post-translational Protein Modification
Pathways		Chromatin modifying enzymes	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Citrulline
Diseases
GWAS		Basal cell carcinoma ( 24403052 25855136 18849993) Mean platelet volume ( 27863252)	Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)
Interacting Genes		3 interacting genes: KLHL2 SUV39H1 ZNF526	31 interacting genes: ACTC1 BCAM BYSL C20orf85 CCDC43 CDC37 CLK2 CUL3 CWC22 ELOA KEAP1 KLHL12 KLHL3 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114
Entrez ID		353238	11275
HPRD ID		15095	09311
Ensembl ID		ENSG00000276747	ENSG00000109466
Uniprot IDs		Q6TGC4	B4DFZ5 E9PEX9 O95198
PDB IDs		4DAT 4DAU	2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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