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IGFBP5 and GOLM1
Data Source:
BioGRID
(two hybrid)
IGFBP5
GOLM1
Description
insulin like growth factor binding protein 5
golgi membrane protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Lumen
Insulin-like Growth Factor Binding Protein Complex
Insulin-like Growth Factor Ternary Complex
Extracellular Space
Endoplasmic Reticulum Lumen
Golgi Apparatus
Integral Component Of Plasma Membrane
Molecular Function
Fibronectin Binding
Protein Binding
Insulin-like Growth Factor I Binding
Insulin-like Growth Factor II Binding
Protein Binding
Biological Process
Regulation Of Cell Growth
Osteoblast Differentiation
Signal Transduction
Female Pregnancy
Aging
Negative Regulation Of Smooth Muscle Cell Migration
Negative Regulation Of Translation
Negative Regulation Of Cell Migration
Hair Follicle Morphogenesis
Intracellular Signal Transduction
Glucose Homeostasis
Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Post-translational Protein Modification
Cellular Protein Metabolic Process
Type B Pancreatic Cell Proliferation
Negative Regulation Of Osteoblast Differentiation
Negative Regulation Of Growth
Lung Alveolus Development
Negative Regulation Of Smooth Muscle Cell Proliferation
Striated Muscle Cell Differentiation
Positive Regulation Of Protein Kinase B Signaling
Mammary Gland Involution
Response To Growth Hormone
Cellular Response To CAMP
Cellular Response To Organic Cyclic Compound
Negative Regulation Of Muscle Tissue Development
Negative Regulation Of Skeletal Muscle Hypertrophy
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration
Nucleus Organization
Regulation Of Lipid Metabolic Process
Post-translational Protein Modification
Cellular Protein Metabolic Process
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Drugs
Diseases
GWAS
Blood protein levels (
30072576
29875488
)
Breast cancer (
29059683
)
Creatinine levels (
29403010
)
Estimated glomerular filtration rate (
30604766
)
FEV1 (
30804560
)
Glomerular filtration rate (
27588450
29403010
)
Glomerular filtration rate in non diabetics (creatinine) (
26831199
)
Height (
31562340
)
Hypothyroidism (
27182965
)
Lung function (FEV1/FVC) (
30804560
)
Metabolite levels (
23823483
)
Mitral valve prolapse (
26301497
)
Pulse pressure (
27841878
)
Serum thyroid-stimulating hormone levels (
25436638
)
Thyroid hormone levels (
23408906
)
Thyroid stimulating hormone levels (
32769997
)
Visceral fat (
22589738
)
Blood protein levels (
30072576
)
Logical memory (delayed recall) in normal cognition (
29274321
)
Interacting Genes
92 interacting genes:
ABHD4
ADAM12
AHNAK2
AMIGO1
ANKS6
APH1A
AQP2
AQP6
AQP9
ASGR1
BAG6
BSND
CD53
CERS4
CHODL
CLDN2
CLDN20
CLDN6
CLDN7
CLDN9
CLEC17A
CREB3
CXCR1
ELOVL5
ERGIC3
F2
FAM209A
FCRL3
FHL1
FHL2
FN1
FNDC9
GJA5
GJA8
GJB3
GJB5
GOLM1
GPR151
GPR152
GPR37L1
GPR42
GPRC5D
GPX8
HSD17B13
IGF1
IGF2
IGFALS
KCNK5
KIAA2013
KPNB1
LAPTM4B
LAYN
LDLRAD1
LHFPL1
LMNA
LTBP1
MFF
MFSD5
MRPS18B
MS4A3
MS4A7
NCAPH2
PAPPA2
PDZK1IP1
PNO1
PROKR2
RASSF1
RHCG
SERPINE1
SLC10A6
SLC13A4
SLC38A1
SLC41A2
SLC41A3
SPAG4
SPP1
SYNE4
TF
THAP4
THBS1
TLCD4
TMEM106A
TMEM106C
TMEM179B
TMEM237
TMEM45A
TMEM52B
TMPRSS2
TMX2
TSPAN12
TSPO2
VTN
76 interacting genes:
ABI3
AIG1
ANKRD46
ASPH
B3GNT4
BCL2L1
C1orf174
C1QL4
CDIPT
CIAO1
CLDN4
CLDND2
CLK1
CNPY3
DCK
DCTN2
DESI1
DEXI
EFTUD2
EIF2B3
EIF3J
ELAC2
FLOT1
FTH1
FUT9
GALNT15
GAST
GEMIN7
GET3
GLB1
GRIK5
GUCA2A
HGFAC
HSD17B13
IGFBP5
INSIG2
JAGN1
KCNE3
LAT
LSM12
MED22
MIP
NDUFV2
NEU1
NINJ1
NIPSNAP3A
NRSN2
PGRMC1
RACK1
RIPPLY2
RPA2
RPL13A
SFTPC
SLC13A5
SLC30A3
SLC35B2
SLC40A1
SLC5A4
SLCO3A1
ST6GAL2
STRIT1
SYT1
TF
THSD7A
TMEM109
TMEM140
TMEM147
TMEM176A
TMEM86B
TMEM98
TMPO
TMUB1
TMUB2
TSG101
VSTM1
ZFAND3
Entrez ID
3488
51280
HPRD ID
00901
08428
Ensembl ID
ENSG00000115461
ENSG00000135052
Uniprot IDs
P24593
B3KNK9
Q8NBJ4
PDB IDs
1BOE
1H59
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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