IGFBP5 and PAPPA2

  • Data Source:
  • HPRD (in vitro)

IGFBP5

PAPPA2

Description insulin like growth factor binding protein 5 pappalysin 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Automobile speeding propensity ( 30643258)
  • Birth weight ( 31043758)
  • Body mass index ( 26426971)
  • Fractional exhaled nitric oxide (childhood) ( 24315451)
  • GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273)
  • Height ( 20881960 25429064 31562340)
  • Offspring birth weight ( 31043758)
  • Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407)
  • Pulse pressure ( 27841878 30578418)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500)
  • Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes 92 interacting genes: ABHD4 ADAM12 AHNAK2 AMIGO1 ANKS6 APH1A AQP2 AQP6 AQP9 ASGR1 BAG6 BSND CD53 CERS4 CHODL CLDN2 CLDN20 CLDN6 CLDN7 CLDN9 CLEC17A CREB3 CXCR1 ELOVL5 ERGIC3 F2 FAM209A FCRL3 FHL1 FHL2 FN1 FNDC9 GJA5 GJA8 GJB3 GJB5 GOLM1 GPR151 GPR152 GPR37L1 GPR42 GPRC5D GPX8 HSD17B13 IGF1 IGF2 IGFALS KCNK5 KIAA2013 KPNB1 LAPTM4B LAYN LDLRAD1 LHFPL1 LMNA LTBP1 MFF MFSD5 MRPS18B MS4A3 MS4A7 NCAPH2 PAPPA2 PDZK1IP1 PNO1 PROKR2 RASSF1 RHCG SERPINE1 SLC10A6 SLC13A4 SLC38A1 SLC41A2 SLC41A3 SPAG4 SPP1 SYNE4 TF THAP4 THBS1 TLCD4 TMEM106A TMEM106C TMEM179B TMEM237 TMEM45A TMEM52B TMPRSS2 TMX2 TSPAN12 TSPO2 VTN 5 interacting genes: ATF7IP IGFBP3 IGFBP5 SMAD4 ZNF512B
Entrez ID 3488 60676
HPRD ID 00901 10156
Ensembl ID ENSG00000115461 ENSG00000116183
Uniprot IDs P24593 Q9BXP8
PDB IDs 1BOE 1H59
Enriched GO Terms of Interacting Partners?
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