SCHIP1 and HTR6

Data Source:
BioGRID (two hybrid)

		SCHIP1	HTR6
Description		schwannomin interacting protein 1	5-hydroxytryptamine receptor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell Junction	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite Synapse
	Molecular Function	Protein Binding Identical Protein Binding	Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity
	Biological Process	Positive Regulation Of Hippo Signaling	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways			Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Ziprasidone Amitriptyline Olanzapine Clozapine Loxapine Imipramine Chlorpromazine Haloperidol Amoxapine Paroxetine Cyclobenzaprine Ergoloid mesylate Doxepin Quetiapine Aripiprazole Chlorprothixene Dimethyltryptamine Lysergic acid diethylamide Iloperidone SGS518 PRX-07034 SUVN-502 Sertindole Mianserin Asenapine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Bone mineral density (hip) ( 30172743) Celiac disease ( 22057235 25920553 18311140) Congenital heart disease (maternal effect) ( 28468790) Conotruncal heart defects (maternal effects) ( 28468790) Eosinophil counts ( 32888494) Iron status biomarkers (total iron binding capacity) ( 28334935) Limited cutaneous systemic scleroderma ( 24387989) Major depressive disorder ( 23377640) Myeloproliferative neoplasms ( 33057200) Primary biliary cholangitis ( 26394269) Quantitative traits ( 19197348) Self-reported childhood asthma in adult smokers ( 30373671) Systemic sclerosis ( 24387989) Upper eyelid morphology ( 29921221)	Chronotype ( 26955885 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 27494321)
Interacting Genes		11 interacting genes: FOS HTR6 NF2 PRPF18 PSMD4 PTMS SCOC SMARCD1 SYCE1L TMSB4X ZC3H13	31 interacting genes: ABCA2 ACTB AIP AKR1A1 AP2M1 AP4S1 ATXN10 CHN1 CMSS1 COPS5 DDRGK1 DHRS1 EIF4A3 FYN GNAQ GNAS HDGFL2 IDS MAP1B NF1 NRXN3 PARP8 RUNDC3A SCHIP1 SLC6A1 SRRT SYT5 THY1 TMEM98 TTYH1 UQCRFS1
Entrez ID		29970	3362
HPRD ID		15302	03066
Ensembl ID		ENSG00000151967	ENSG00000158748
Uniprot IDs		P0DPB3	P50406
PDB IDs
Enriched GO Terms of Interacting Partners?
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