SCHIP1 and TMSB4X

Data Source:
BioGRID (pull down)

		SCHIP1	TMSB4X
Description		schwannomin interacting protein 1	thymosin beta 4 X-linked
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell Junction	Extracellular Region Nucleus Cytoplasm Cytosol Cytoskeleton Platelet Alpha Granule Lumen
	Molecular Function	Protein Binding Identical Protein Binding	RNA Binding Actin Monomer Binding Protein Binding Enzyme Binding
	Biological Process	Positive Regulation Of Hippo Signaling	Platelet Degranulation Actin Filament Organization Cytoplasmic Sequestering Of NF-kappaB Regulation Of Cell Migration Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-8 Production Tumor Necrosis Factor-mediated Signaling Pathway Sequestering Of Actin Monomers Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Inflammatory Response Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proton-transporting ATP Synthase Activity, Rotational Mechanism Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of ATP Biosynthetic Process
Pathways			Platelet degranulation
Drugs
Diseases
GWAS		Bone mineral density (hip) ( 30172743) Celiac disease ( 22057235 25920553 18311140) Congenital heart disease (maternal effect) ( 28468790) Conotruncal heart defects (maternal effects) ( 28468790) Eosinophil counts ( 32888494) Iron status biomarkers (total iron binding capacity) ( 28334935) Limited cutaneous systemic scleroderma ( 24387989) Major depressive disorder ( 23377640) Myeloproliferative neoplasms ( 33057200) Primary biliary cholangitis ( 26394269) Quantitative traits ( 19197348) Self-reported childhood asthma in adult smokers ( 30373671) Systemic sclerosis ( 24387989) Upper eyelid morphology ( 29921221)	Asthma ( 30929738) Asthma (childhood onset) ( 30929738)
Interacting Genes		11 interacting genes: FOS HTR6 NF2 PRPF18 PSMD4 PTMS SCOC SMARCD1 SYCE1L TMSB4X ZC3H13	38 interacting genes: ACTA1 ACTA2 ACTB ACTG1 AKAP8L ALAS1 ANXA7 APLP1 CDKN1A COG6 FAM118B FHL3 GOLGA6L9 GRB7 HSF2BP IGSF21 ILK KRT13 KRT15 KRT31 KRT34 KRT36 KRT40 KRTAP8-1 LIMS1 PNMA1 PPP4C RAD21 RBPMS SCHIP1 SMN1 TAF1D TGM2 TK1 TRIM23 TRIM27 TRIP6 UHMK1
Entrez ID		29970	7114
HPRD ID		15302	02153
Ensembl ID		ENSG00000151967	ENSG00000205542
Uniprot IDs		P0DPB3	A2VCK8 P62328 Q0P5T0
PDB IDs			1UY5 3TU5 4PL7 4PL8
Enriched GO Terms of Interacting Partners?
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