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CNOT7 and FHL3
Data Source:
BioGRID
(two hybrid)
CNOT7
FHL3
Description
CCR4-NOT transcription complex subunit 7
four and a half LIM domains 3
Image
GO Annotations
Cellular Component
P-body
Nucleus
Cytoplasm
Cytosol
Membrane
Nuclear Body
Nuclear Speck
CCR4-NOT Complex
CCR4-NOT Core Complex
Stress Fiber
Nucleus
Focal Adhesion
Z Disc
Molecular Function
3'-5'-exoribonuclease Activity
Transcription Corepressor Activity
RNA Binding
Exoribonuclease Activity
Poly(A)-specific Ribonuclease Activity
Protein Binding
Transcription Factor Binding
Metal Ion Binding
Transcription Coregulator Activity
Actin Binding
Protein Binding
Metal Ion Binding
Biological Process
Nuclear-transcribed MRNA Poly(A) Tail Shortening
Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Gene Expression
Negative Regulation Of Translation
Gene Silencing By RNA
P-body Assembly
Gene Silencing By MiRNA
Regulation Of Tyrosine Phosphorylation Of STAT Protein
Exonucleolytic Catabolism Of Deadenylated MRNA
Positive Regulation Of Viral Genome Replication
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Defense Response To Virus
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
Negative Regulation Of Type I Interferon-mediated Signaling Pathway
Positive Regulation Of MRNA Catabolic Process
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Regulation Of Transcription, DNA-templated
Muscle Organ Development
Actin Cytoskeleton Organization
Pathways
Deadenylation of mRNA
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS
Coronary artery disease (
29212778
33020668
)
Pulse pressure (
30578418
)
Interacting Genes
28 interacting genes:
APP
BTG1
BTG2
BTG3
CDK1
CDK2
CDK4
CDK6
CNOT6
FBXO7
FHL3
FOXC2
HOXD4
IKBKG
LSM3
MRFAP1L1
NMI
PABPC1
PIAS1
PSMC1
PSMC2
SCARA3
SH3GLB2
TCP11L1
TEX11
TOB1
TOB2
TSG101
181 interacting genes:
A1CF
ACTB
ADAM15
ADAMTSL4
AIMP2
AMBP
ANKHD1
ARHGEF10
ARID5A
ASCL4
BARX2
C1orf94
C9orf116
CASS4
CBX8
CCDC198
CCND3
CDC25B
CDC42EP1
CDKN1A
CDKN2D
CHEK2
CLCN2
CNNM3
CNOT7
CORO1A
CREB5
CRIP3
CRYBA2
CSF1
CTBP2
CYSRT1
DCDC2B
DLGAP4
DMRT3
DUX4L9
E2F8
EFCAB12
EIF4EBP2
EPHA10
EPM2AIP1
ERBB3
EXOSC1
EXOSC5
FADS6
FAM110A
FAM126A
FAM222B
FAM71C
FAM90A1
FBXL18
FHL2
FOS
FOSL2
FOXN4
GATA1
GATA2
GCM2
GUCD1
HAPLN2
HIPK1
HOXA1
HSF2BP
HYAL2
IHO1
IKZF3
ITGA7
ITGB5
KANK2
KIDINS220
KIRREL2
KLF12
KLF3
KLF8
KPRP
KRTAP12-1
KRTAP12-2
KTI12
LASP1
LATS2
LHB
LMO2
LMO4
LNX1
LNX2
MAPK1
MED15
MMP14
MORF4L1
MPZL1
MRM3
MRPL27
MRRF
MSRB3
MTA1
MTUS2
MYBPC1
MYBPHL
MYOZ3
MYPOP
MZF1
NDUFAB1
NFKBIB
NPRL3
ODF3B
P4HA2
PAK5
PATL1
PHC2
PHF21A
PIAS1
PKP2
PLEKHF2
PLEKHG4B
POLR1H
PPIG
PPP1R32
PRR35
PRR5L
PTPN6
QKI
QRICH1
RAB40B
RAD21
RASL12
RBM42
RFX3
RFX6
RHEBL1
RSPH14
RYBP
SAP30BP
SAXO1
SBF2
SDCBP
SH3GLB2
SHE
SLAIN1
SLC25A46
SLC44A3
SLU7
SMAD2
SMAD3
SMAD4
SNRPB
SNRPC
SNRPG
SPATA8
SREBF2
SRF
SRGN
SUPT5H
TBC1D22B
THAP7
THEG
TLE5
TMEM108
TMEM14B
TMSB4X
TMX3
TOPBP1
TRAF3IP2
TRIM27
TRIP6
TRO
TSGA10IP
TTLL10
TUBA3E
TYK2
TYMSOS
UBE2I
UBE2Q1
VWC2L
WDR25
WNK1
YPEL3
ZCCHC14
ZFP36
ZNF417
ZNF512B
ZNF587
Entrez ID
29883
2275
HPRD ID
05370
09101
Ensembl ID
ENSG00000198791
ENSG00000183386
Uniprot IDs
Q96IQ6
Q9UIV1
Q13643
Q96C98
PDB IDs
2D5R
4GMJ
1WYH
2CUQ
2EHE
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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