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FHL3 and PKP2
Data Source:
BioGRID
(two hybrid)
FHL3
PKP2
Description
four and a half LIM domains 3
plakophilin 2
Image
GO Annotations
Cellular Component
Stress Fiber
Nucleus
Focal Adhesion
Z Disc
Cornified Envelope
Nucleus
Nucleoplasm
Cytoplasm
Intermediate Filament
Plasma Membrane
Cell-cell Junction
Adherens Junction
Intercalated Disc
Integral Component Of Membrane
Cell Junction
Desmosome
Messenger Ribonucleoprotein Complex
Molecular Function
Transcription Coregulator Activity
Actin Binding
Protein Binding
Metal Ion Binding
Protein Kinase C Binding
Protein Binding
Sodium Channel Regulator Activity
Intermediate Filament Binding
Ion Channel Binding
Alpha-catenin Binding
Cadherin Binding
Molecular Adaptor Activity
Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
Biological Process
Regulation Of Transcription, DNA-templated
Muscle Organ Development
Actin Cytoskeleton Organization
Desmosome Assembly
Desmosome Organization
Cell-cell Junction Assembly
Heart Development
Positive Regulation Of Sodium Ion Transport
Keratinization
Intermediate Filament Bundle Assembly
Maintenance Of Animal Organ Identity
Ventricular Cardiac Muscle Tissue Morphogenesis
Cornification
Protein Localization To Plasma Membrane
Cardiac Muscle Cell Action Potential Involved In Contraction
Ventricular Cardiac Muscle Cell Action Potential
Cell-cell Signaling Involved In Cardiac Conduction
Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication
Regulation Of Heart Rate By Cardiac Conduction
Cell-cell Adhesion
Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways
Keratinization
Formation of the cornified envelope
Drugs
Diseases
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
GWAS
Coronary artery disease (
29212778
33020668
)
Pulse pressure (
30578418
)
Atrial fibrillation (
30061737
29892015
)
Blood protein levels (
30072576
)
Body mass index (change over time) in lung cancer (
28044437
)
Methadone dose in opioid dependence (
28115739
)
Obesity-related traits (
23251661
)
Parkinson's disease (
32201043
27182965
)
Periodontal disease related phenotype (PCT5) (
26962152
)
Prevalent atrial fibrillation (
28416818
)
Interacting Genes
181 interacting genes:
A1CF
ACTB
ADAM15
ADAMTSL4
AIMP2
AMBP
ANKHD1
ARHGEF10
ARID5A
ASCL4
BARX2
C1orf94
C9orf116
CASS4
CBX8
CCDC198
CCND3
CDC25B
CDC42EP1
CDKN1A
CDKN2D
CHEK2
CLCN2
CNNM3
CNOT7
CORO1A
CREB5
CRIP3
CRYBA2
CSF1
CTBP2
CYSRT1
DCDC2B
DLGAP4
DMRT3
DUX4L9
E2F8
EFCAB12
EIF4EBP2
EPHA10
EPM2AIP1
ERBB3
EXOSC1
EXOSC5
FADS6
FAM110A
FAM126A
FAM222B
FAM71C
FAM90A1
FBXL18
FHL2
FOS
FOSL2
FOXN4
GATA1
GATA2
GCM2
GUCD1
HAPLN2
HIPK1
HOXA1
HSF2BP
HYAL2
IHO1
IKZF3
ITGA7
ITGB5
KANK2
KIDINS220
KIRREL2
KLF12
KLF3
KLF8
KPRP
KRTAP12-1
KRTAP12-2
KTI12
LASP1
LATS2
LHB
LMO2
LMO4
LNX1
LNX2
MAPK1
MED15
MMP14
MORF4L1
MPZL1
MRM3
MRPL27
MRRF
MSRB3
MTA1
MTUS2
MYBPC1
MYBPHL
MYOZ3
MYPOP
MZF1
NDUFAB1
NFKBIB
NPRL3
ODF3B
P4HA2
PAK5
PATL1
PHC2
PHF21A
PIAS1
PKP2
PLEKHF2
PLEKHG4B
POLR1H
PPIG
PPP1R32
PRR35
PRR5L
PTPN6
QKI
QRICH1
RAB40B
RAD21
RASL12
RBM42
RFX3
RFX6
RHEBL1
RSPH14
RYBP
SAP30BP
SAXO1
SBF2
SDCBP
SH3GLB2
SHE
SLAIN1
SLC25A46
SLC44A3
SLU7
SMAD2
SMAD3
SMAD4
SNRPB
SNRPC
SNRPG
SPATA8
SREBF2
SRF
SRGN
SUPT5H
TBC1D22B
THAP7
THEG
TLE5
TMEM108
TMEM14B
TMSB4X
TMX3
TOPBP1
TRAF3IP2
TRIM27
TRIP6
TRO
TSGA10IP
TTLL10
TUBA3E
TYK2
TYMSOS
UBE2I
UBE2Q1
VWC2L
WDR25
WNK1
YPEL3
ZCCHC14
ZFP36
ZNF417
ZNF512B
ZNF587
40 interacting genes:
ACTN3
AKAP9
CARD9
CASK
CCDC120
CCDC125
CCHCR1
CTNNB1
DMRTB1
DSC1
DSC2
DSG1
DSG2
DSP
FHL3
GOLGA2
GRIPAP1
GTF2IRD1
HOOK2
HSPB2
JUP
KLC4
KRT18
KRT31
KRT5
MAGOHB
MARK3
MTUS2
NCKIPSD
NDEL1
PIBF1
PLEKHG4
POLR3A
RABEP1
RBM5
ROPN1
SMAD9
SPTA1
TEKT4
YWHAG
Entrez ID
2275
5318
HPRD ID
09101
04177
Ensembl ID
ENSG00000183386
ENSG00000057294
Uniprot IDs
Q13643
Q96C98
Q99959
PDB IDs
1WYH
2CUQ
2EHE
3TT9
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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