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FHL3 and PIAS1
Data Source:
BioGRID
(two hybrid)
FHL3
PIAS1
Description
four and a half LIM domains 3
protein inhibitor of activated STAT 1
Image
GO Annotations
Cellular Component
Stress Fiber
Nucleus
Focal Adhesion
Z Disc
Nucleus
Nucleoplasm
PML Body
Nuclear Speck
Molecular Function
Transcription Coregulator Activity
Actin Binding
Protein Binding
Metal Ion Binding
RNA Polymerase II Transcription Factor Binding
DNA Binding
Transcription Coregulator Activity
Transcription Corepressor Activity
Protein Binding
Protein C-terminus Binding
Zinc Ion Binding
SUMO Transferase Activity
Enzyme Binding
Protein Domain Specific Binding
Ubiquitin Protein Ligase Binding
SUMO Ligase Activity
Biological Process
Regulation Of Transcription, DNA-templated
Muscle Organ Development
Actin Cytoskeleton Organization
G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Receptor Signaling Pathway Via JAK-STAT
Spermatogenesis
Visual Learning
Protein Sumoylation
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Sumoylation
Regulation Of Cell Population Proliferation
Negative Regulation Of Apoptotic Process
Fat Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Smooth Muscle Cell Differentiation
Regulation Of Interferon-gamma-mediated Signaling Pathway
Protein-DNA Complex Assembly
Pathways
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of ubiquitinylation proteins
SUMOylation of transcription cofactors
SUMOylation of intracellular receptors
SUMOylation of intracellular receptors
SUMOylation of chromatin organization proteins
Formation of Incision Complex in GG-NER
Regulation of IFNG signaling
Drugs
Diseases
GWAS
Coronary artery disease (
29212778
33020668
)
Pulse pressure (
30578418
)
Diastolic blood pressure (
30224653
)
Diverticular disease (
30177863
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Major depressive disorder (
23377640
)
Number of twin births (
30760885
)
Interacting Genes
181 interacting genes:
A1CF
ACTB
ADAM15
ADAMTSL4
AIMP2
AMBP
ANKHD1
ARHGEF10
ARID5A
ASCL4
BARX2
C1orf94
C9orf116
CASS4
CBX8
CCDC198
CCND3
CDC25B
CDC42EP1
CDKN1A
CDKN2D
CHEK2
CLCN2
CNNM3
CNOT7
CORO1A
CREB5
CRIP3
CRYBA2
CSF1
CTBP2
CYSRT1
DCDC2B
DLGAP4
DMRT3
DUX4L9
E2F8
EFCAB12
EIF4EBP2
EPHA10
EPM2AIP1
ERBB3
EXOSC1
EXOSC5
FADS6
FAM110A
FAM126A
FAM222B
FAM71C
FAM90A1
FBXL18
FHL2
FOS
FOSL2
FOXN4
GATA1
GATA2
GCM2
GUCD1
HAPLN2
HIPK1
HOXA1
HSF2BP
HYAL2
IHO1
IKZF3
ITGA7
ITGB5
KANK2
KIDINS220
KIRREL2
KLF12
KLF3
KLF8
KPRP
KRTAP12-1
KRTAP12-2
KTI12
LASP1
LATS2
LHB
LMO2
LMO4
LNX1
LNX2
MAPK1
MED15
MMP14
MORF4L1
MPZL1
MRM3
MRPL27
MRRF
MSRB3
MTA1
MTUS2
MYBPC1
MYBPHL
MYOZ3
MYPOP
MZF1
NDUFAB1
NFKBIB
NPRL3
ODF3B
P4HA2
PAK5
PATL1
PHC2
PHF21A
PIAS1
PKP2
PLEKHF2
PLEKHG4B
POLR1H
PPIG
PPP1R32
PRR35
PRR5L
PTPN6
QKI
QRICH1
RAB40B
RAD21
RASL12
RBM42
RFX3
RFX6
RHEBL1
RSPH14
RYBP
SAP30BP
SAXO1
SBF2
SDCBP
SH3GLB2
SHE
SLAIN1
SLC25A46
SLC44A3
SLU7
SMAD2
SMAD3
SMAD4
SNRPB
SNRPC
SNRPG
SPATA8
SREBF2
SRF
SRGN
SUPT5H
TBC1D22B
THAP7
THEG
TLE5
TMEM108
TMEM14B
TMSB4X
TMX3
TOPBP1
TRAF3IP2
TRIM27
TRIP6
TRO
TSGA10IP
TTLL10
TUBA3E
TYK2
TYMSOS
UBE2I
UBE2Q1
VWC2L
WDR25
WNK1
YPEL3
ZCCHC14
ZFP36
ZNF417
ZNF512B
ZNF587
107 interacting genes:
AKT1
AR
ATXN1
AXIN1
BARD1
BRCA1
CASP8
CBS
CDK4
CEBPA
CEBPE
CHUK
CNOT7
CREB1
CREBBP
CSNK2A1
CSRP2
DCLRE1A
DDX21
DDX5
DNM1
DNMT3A
ELK3
EP300
ESR1
ESR2
FANCI
FHL3
FLI1
GATA4
GLUL
GRM8
GSK3B
GTF2IRD1
HECTD2
HIC1
HTT
IKZF5
JUN
KLF3
L3MBTL2
LSM3
MAML1
MBD1
MDC1
MDM2
MITF
MSX1
MX1
MYB
NCOR1
NFATC1
NIN
NR2F2
NR3C2
NR5A1
PAXIP1
PGR
PIAS2
PIAS4
PLAG1
PML
PPP1CA
PPP1CC
PRDM1
PRPF40A
PSME3
PTK2
PTPN1
QKI
RAD54L2
RBBP6
RELA
SATB1
SATB2
SERBP1
SGTA
SKIL
SMAD1
SMAD4
SMAD7
SNAI2
SNIP1
SP3
SPOP
SREBF2
STAT1
SUFU
SUMO1
SUMO1P1
SUMO2
SUMO3
TBP
TERF2
TEX11
TP53
TP73
TRIM27
TRIM5
TRIM55
TRIM63
TSG101
UBE2I
UBE2L3
YWHAZ
ZNF451
ZNF76
Entrez ID
2275
8554
HPRD ID
09101
16029
Ensembl ID
ENSG00000183386
ENSG00000033800
Uniprot IDs
Q13643
Q96C98
O75925
Q1XBU8
PDB IDs
1WYH
2CUQ
2EHE
1V66
Enriched GO Terms of Interacting Partners
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