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RACGAP1 and PRC1
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(two hybrid, in vivo, in vitro)
RACGAP1
PRC1
Description
Rac GTPase activating protein 1
protein regulator of cytokinesis 1
Image
GO Annotations
Cellular Component
Acrosomal Vesicle
Nucleus
Nucleoplasm
Spindle
Cytosol
Microtubule
Midbody
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Cleavage Furrow
Spindle Midzone
Extracellular Exosome
Mitotic Spindle
Flemming Body
Centralspindlin Complex
Spindle Pole
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Spindle
Cytosol
Spindle Microtubule
Plasma Membrane
Microtubule Cytoskeleton
Midbody
Intercellular Bridge
Contractile Ring
Mitotic Spindle Midzone
Molecular Function
GTPase Activator Activity
Protein Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Microtubule Binding
Protein Kinase Binding
Alpha-tubulin Binding
Gamma-tubulin Binding
Metal Ion Binding
Beta-tubulin Binding
Protein Binding
Microtubule Binding
Kinesin Binding
Protein Kinase Binding
Biological Process
Mitotic Cytokinesis
Actomyosin Contractile Ring Assembly
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Microtubule-based Movement
Spermatogenesis
Neuroblast Proliferation
Sulfate Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of Cytokinesis
Intracellular Signal Transduction
Positive Regulation Of GTPase Activity
Regulation Of Embryonic Development
Regulation Of Small GTPase Mediated Signal Transduction
Mitotic Spindle Midzone Assembly
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Mitotic Spindle Elongation
Microtubule Cytoskeleton Organization
Microtubule Bundle Formation
Positive Regulation Of Cell Population Proliferation
Regulation Of Cytokinesis
Mitotic Spindle Midzone Assembly
Cell Division
Pathways
Rho GTPase cycle
MHC class II antigen presentation
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins
RHO GTPases activate CIT
Drugs
Diseases
GWAS
Breast cancer (
29059683
25038754
)
Mean platelet volume (
32888494
27863252
)
Multisite chronic pain (
31194737
)
Red cell distribution width (
32888494
)
Type 2 diabetes (
22885922
24509480
30054458
30297969
26818947
32499647
20581827
30718926
28869590
)
Interacting Genes
32 interacting genes:
AURKB
BYSL
CDK1
CDK3
CHN2
ECT2
HIF1A
KIF23
MAP3K10
MAP3K4
MORF4L1
MPRIP
NRAS
PLK1
PPP2CA
PPP2R5E
PRC1
PRSS23
PTPA
RAC1
RND2
SH3RF1
SLC16A10
SLC26A8
TANK
TRAF3IP3
TUBA4A
TUBG1
TXNDC11
VAV1
YWHAB
YWHAG
29 interacting genes:
AKAP9
CASK
CCDC85B
CCNA2
CCNB1
CCNE1
CDK1
CDK2
CINP
FXR2
KIF3B
KIF4A
KLC2
KLC4
KRT20
MAT2A
NDEL1
PCM1
PKIA
PLK1
RACGAP1
RBM10
RPA2
SF3B2
SLAIN1
SUMO2
TRIM37
USHBP1
YWHAE
Entrez ID
29127
9055
HPRD ID
05402
17899
Ensembl ID
ENSG00000161800
ENSG00000198901
Uniprot IDs
A0A024R136
B2RE34
Q9H0H5
A0A024RC67
O43663
PDB IDs
2OVJ
3W6R
3WPQ
3WPS
4B6D
5C2J
5C2K
3NRX
3NRY
4L3I
4L6Y
5KMG
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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