PRC1 and MAT2A

Data Source:
BioGRID (two hybrid)

		PRC1	MAT2A
Description		protein regulator of cytokinesis 1	methionine adenosyltransferase 2A
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GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Chromosome Cytoplasm Spindle Cytosol Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton Midbody Intercellular Bridge Contractile Ring Mitotic Spindle Midzone	Cytosol Methionine Adenosyltransferase Complex
	Molecular Function	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding	Methionine Adenosyltransferase Activity Protein Binding ATP Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Mitotic Spindle Elongation Microtubule Cytoskeleton Organization Microtubule Bundle Formation Positive Regulation Of Cell Population Proliferation Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly Cell Division	S-adenosylmethionine Biosynthetic Process One-carbon Metabolic Process Methylation Protein Hexamerization Protein Heterooligomerization Cellular Response To Leukemia Inhibitory Factor
Pathways		RHO GTPases activate CIT	Methylation
Drugs			Ademetionine
Diseases
GWAS		Breast cancer ( 29059683 25038754) Mean platelet volume ( 32888494 27863252) Multisite chronic pain ( 31194737) Red cell distribution width ( 32888494) Type 2 diabetes ( 22885922 24509480 30054458 30297969 26818947 32499647 20581827 30718926 28869590)	Coronary artery disease ( 29212778 30104761) Dysmenorrheic pain ( 27454463) Urinary albumin excretion ( 30220432)
Interacting Genes		29 interacting genes: AKAP9 CASK CCDC85B CCNA2 CCNB1 CCNE1 CDK1 CDK2 CINP FXR2 KIF3B KIF4A KLC2 KLC4 KRT20 MAT2A NDEL1 PCM1 PKIA PLK1 RACGAP1 RBM10 RPA2 SF3B2 SLAIN1 SUMO2 TRIM37 USHBP1 YWHAE	7 interacting genes: CUL3 HGS MAT1A MAT2B PRC1 TMEM213 UBE2I
Entrez ID		9055	4144
HPRD ID		17899	03275
Ensembl ID		ENSG00000198901	ENSG00000168906
Uniprot IDs		A0A024RC67 O43663	A0A140VJP5 P31153
PDB IDs		3NRX 3NRY 4L3I 4L6Y 5KMG	2P02 4KTT 4KTV 4NDN 5A19 5A1G 5A1I 5UGH 6FAJ 6FBN 6FBO 6FBP 6FCB 6FCD 6FWB 6G6R 6P9V
Enriched GO Terms of Interacting Partners?
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