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RACGAP1 and PTPA
Data Source:
BioGRID
(pull down, enzymatic study)
RACGAP1
PTPA
Description
Rac GTPase activating protein 1
protein phosphatase 2 phosphatase activator
Image
GO Annotations
Cellular Component
Acrosomal Vesicle
Nucleus
Nucleoplasm
Spindle
Cytosol
Microtubule
Midbody
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Cleavage Furrow
Spindle Midzone
Extracellular Exosome
Mitotic Spindle
Flemming Body
Centralspindlin Complex
Protein Phosphatase Type 2A Complex
Nucleus
Nucleoplasm
Cytoplasm
Calcium Channel Complex
Extracellular Exosome
Molecular Function
GTPase Activator Activity
Protein Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Microtubule Binding
Protein Kinase Binding
Alpha-tubulin Binding
Gamma-tubulin Binding
Metal Ion Binding
Beta-tubulin Binding
Peptidyl-prolyl Cis-trans Isomerase Activity
Signaling Receptor Binding
Protein Binding
ATP Binding
Protein Tyrosine Phosphatase Activator Activity
ATPase Activity
Protein Phosphatase Regulator Activity
Protein Homodimerization Activity
Protein Phosphatase 2A Binding
Biological Process
Mitotic Cytokinesis
Actomyosin Contractile Ring Assembly
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Microtubule-based Movement
Spermatogenesis
Neuroblast Proliferation
Sulfate Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of Cytokinesis
Intracellular Signal Transduction
Positive Regulation Of GTPase Activity
Regulation Of Embryonic Development
Regulation Of Small GTPase Mediated Signal Transduction
Mitotic Spindle Midzone Assembly
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Protein Peptidyl-prolyl Isomerization
Mitotic Spindle Organization
Negative Regulation Of Phosphoprotein Phosphatase Activity
Positive Regulation Of Phosphoprotein Phosphatase Activity
Positive Regulation Of Protein Dephosphorylation
Negative Regulation Of Protein Dephosphorylation
Positive Regulation Of Apoptotic Process
Regulation Of Phosphoprotein Phosphatase Activity
Pathways
Rho GTPase cycle
MHC class II antigen presentation
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins
Drugs
Diseases
GWAS
Interacting Genes
32 interacting genes:
AURKB
BYSL
CDK1
CDK3
CHN2
ECT2
HIF1A
KIF23
MAP3K10
MAP3K4
MORF4L1
MPRIP
NRAS
PLK1
PPP2CA
PPP2R5E
PRC1
PRSS23
PTPA
RAC1
RND2
SH3RF1
SLC16A10
SLC26A8
TANK
TRAF3IP3
TUBA4A
TUBG1
TXNDC11
VAV1
YWHAB
YWHAG
28 interacting genes:
AKT1
AMOT
APP
AURKB
CCDC125
CCNE1
CCNG1
CCNG2
CSNK2A1
CYLD
DTD1
EIF4EBP1
F3
FOXO3
GRIN3A
H2AX
HDAC4
KISS1R
MAPT
MID1
NIF3L1
PPP2R1A
PPP2R3A
PRKCB
RACGAP1
SPG21
SRC
SULT4A1
Entrez ID
29127
5524
HPRD ID
05402
02858
Ensembl ID
ENSG00000161800
ENSG00000119383
Uniprot IDs
A0A024R136
B2RE34
Q9H0H5
B4DZF8
F6WIT2
Q15257
PDB IDs
2OVJ
3W6R
3WPQ
3WPS
4B6D
5C2J
5C2K
2G62
2HV6
2HV7
2IXM
4LAC
4NY3
Enriched GO Terms of Interacting Partners
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