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RACGAP1 and TUBG1
Data Source:
HPRD
(in vivo)
RACGAP1
TUBG1
Description
Rac GTPase activating protein 1
tubulin gamma 1
Image
GO Annotations
Cellular Component
Acrosomal Vesicle
Nucleus
Nucleoplasm
Spindle
Cytosol
Microtubule
Midbody
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Cleavage Furrow
Spindle Midzone
Extracellular Exosome
Mitotic Spindle
Flemming Body
Centralspindlin Complex
Condensed Nuclear Chromosome
Gamma-tubulin Complex
Nucleus
Cytoplasm
Centrosome
Spindle
Polar Microtubule
Cytosol
Microtubule
Recycling Endosome
Mitotic Spindle Microtubule
Molecular Function
GTPase Activator Activity
Protein Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Microtubule Binding
Protein Kinase Binding
Alpha-tubulin Binding
Gamma-tubulin Binding
Metal Ion Binding
Beta-tubulin Binding
GTPase Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Identical Protein Binding
Biological Process
Mitotic Cytokinesis
Actomyosin Contractile Ring Assembly
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Microtubule-based Movement
Spermatogenesis
Neuroblast Proliferation
Sulfate Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of Cytokinesis
Intracellular Signal Transduction
Positive Regulation Of GTPase Activity
Regulation Of Embryonic Development
Regulation Of Small GTPase Mediated Signal Transduction
Mitotic Spindle Midzone Assembly
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Mitotic Sister Chromatid Segregation
G2/M Transition Of Mitotic Cell Cycle
Meiotic Spindle Organization
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Microtubule Nucleation
Mitotic Spindle Organization
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cytoplasmic Microtubule Organization
Ciliary Basal Body-plasma Membrane Docking
Pathways
Rho GTPase cycle
MHC class II antigen presentation
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Vinblastine
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Interacting Genes
32 interacting genes:
AURKB
BYSL
CDK1
CDK3
CHN2
ECT2
HIF1A
KIF23
MAP3K10
MAP3K4
MORF4L1
MPRIP
NRAS
PLK1
PPP2CA
PPP2R5E
PRC1
PRSS23
PTPA
RAC1
RND2
SH3RF1
SLC16A10
SLC26A8
TANK
TRAF3IP3
TUBA4A
TUBG1
TXNDC11
VAV1
YWHAB
YWHAG
28 interacting genes:
APP
BRCA1
CENPJ
CNTN2
CUL4A
DDX41
IKBKG
KIF14
KRT18
KRT19
MARK4
NAPG
NDE1
PCNT
PIK3R1
PLK1
PXN
RACGAP1
RACK1
RASSF1
RNF19A
RPGR
SPATC1
TUBA1B
TUBA3C
TUBB4B
TUBGCP3
TUBGCP4
Entrez ID
29127
7283
HPRD ID
05402
01853
Ensembl ID
ENSG00000161800
ENSG00000131462
Uniprot IDs
A0A024R136
B2RE34
Q9H0H5
P23258
PDB IDs
2OVJ
3W6R
3WPQ
3WPS
4B6D
5C2J
5C2K
1Z5V
1Z5W
3CB2
6V5V
6V6S
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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