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RACGAP1 and MPRIP
Data Source:
BioGRID
(two hybrid)
RACGAP1
MPRIP
Description
Rac GTPase activating protein 1
myosin phosphatase Rho interacting protein
Image
No pdb structure
GO Annotations
Cellular Component
Acrosomal Vesicle
Nucleus
Nucleoplasm
Spindle
Cytosol
Microtubule
Midbody
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Cleavage Furrow
Spindle Midzone
Extracellular Exosome
Mitotic Spindle
Flemming Body
Centralspindlin Complex
Cytosol
Focal Adhesion
Actin Cytoskeleton
Molecular Function
GTPase Activator Activity
Protein Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Microtubule Binding
Protein Kinase Binding
Alpha-tubulin Binding
Gamma-tubulin Binding
Metal Ion Binding
Beta-tubulin Binding
Protein Binding
Cadherin Binding
Actin Filament Binding
Biological Process
Mitotic Cytokinesis
Actomyosin Contractile Ring Assembly
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Microtubule-based Movement
Spermatogenesis
Neuroblast Proliferation
Sulfate Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of Cytokinesis
Intracellular Signal Transduction
Positive Regulation Of GTPase Activity
Regulation Of Embryonic Development
Regulation Of Small GTPase Mediated Signal Transduction
Mitotic Spindle Midzone Assembly
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Actin Filament Organization
Pathways
Rho GTPase cycle
MHC class II antigen presentation
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins
Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS
Diabetic retinopathy (
21441570
)
Estimated glomerular filtration rate (
31152163
)
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
Obesity-related traits (
23251661
)
Interacting Genes
32 interacting genes:
AURKB
BYSL
CDK1
CDK3
CHN2
ECT2
HIF1A
KIF23
MAP3K10
MAP3K4
MORF4L1
MPRIP
NRAS
PLK1
PPP2CA
PPP2R5E
PRC1
PRSS23
PTPA
RAC1
RND2
SH3RF1
SLC16A10
SLC26A8
TANK
TRAF3IP3
TUBA4A
TUBG1
TXNDC11
VAV1
YWHAB
YWHAG
14 interacting genes:
ATXN7
IKBKG
LSM8
NOS3
PIAS4
PPP1R12A
PPP1R12C
PTEN
RACGAP1
RHOA
YTHDC1
YWHAB
YWHAG
YWHAQ
Entrez ID
29127
23164
HPRD ID
05402
17591
Ensembl ID
ENSG00000161800
ENSG00000133030
Uniprot IDs
A0A024R136
B2RE34
Q9H0H5
Q6WCQ1
Q8N236
PDB IDs
2OVJ
3W6R
3WPQ
3WPS
4B6D
5C2J
5C2K
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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