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HAP1 and PPOX
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
HAP1
PPOX
Description
huntingtin associated protein 1
protoporphyrinogen oxidase
Image
No pdb structure
GO Annotations
Cellular Component
Nucleolus
Mitochondrion
Lysosome
Early Endosome
Autophagosome
Endoplasmic Reticulum
Centrosome
Centriole
Cytosol
Cytoskeleton
Synaptic Vesicle
Actin Cytoskeleton
Inclusion Body
Dendrite
Growth Cone
Cytoplasmic Vesicle
Dendritic Spine
Axon Cytoplasm
Mitochondrial Intermembrane Space
Intrinsic Component Of Mitochondrial Inner Membrane
Integral Component Of Mitochondrial Inner Membrane
Mitochondrial Membrane
Molecular Function
Signaling Receptor Binding
Protein Binding
Myosin Binding
Ion Channel Binding
Brain-derived Neurotrophic Factor Binding
Oxygen-dependent Protoporphyrinogen Oxidase Activity
Oxidoreductase Activity
Flavin Adenine Dinucleotide Binding
Biological Process
Protein Targeting
Exocytosis
Autophagy
Chemical Synaptic Transmission
Brain Development
Anterograde Axonal Transport
Retrograde Axonal Transport
Protein Localization
Regulation Of Exocytosis
Cerebellum Development
Hypothalamus Cell Differentiation
Neurogenesis
Cell Projection Organization
Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Positive Regulation Of Synaptic Transmission, GABAergic
Positive Regulation Of Neurotrophin Production
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Vesicle Transport Along Microtubule
Neurotrophin TRK Receptor Signaling Pathway
Mitochondrion Distribution
Positive Regulation Of Neurogenesis
Anterograde Axonal Transport Of Mitochondrion
Negative Regulation Of Amyloid-beta Formation
Regulation Of Organelle Transport Along Microtubule
Positive Regulation Of Non-motile Cilium Assembly
Porphyrin-containing Compound Biosynthetic Process
Protoporphyrinogen IX Biosynthetic Process
Heme Biosynthetic Process
Response To Drug
Pathways
Heme biosynthesis
Drugs
Diseases
Hepatic porphyria, including: Porphyria Cutanea Tarda (PCT); VHepatoerythropoietic porphyria; Acute Intermittent Porphyria (AIP); Variegate porphyria (VP); ALA-dehydratase deficiency porphyria (ALADP); Hereditary Coproporphyria (HCP)
GWAS
Developmental language disorder (syntactic complexity) (
27016271
)
Esophageal cancer (squamous cell) (
22960999
)
Interacting Genes
93 interacting genes:
AEN
ANTKMT
APLP1
ATP5MF
BARD1
BRD7
C1orf216
C2CD6
C7orf25
C8orf33
CBX8
CCDC113
CCDC13
CDC73
CDK18
CDK5RAP2
COL9A2
CRIP1
DCTN1
DDX49
DEFB1
EIF3E
FAM50B
FEZ1
GABARAPL2
GADD45G
GIT1
GPRASP2
HDAC4
HGS
HMOX2
HOXB5
HSPA1A
HSPA4
HTT
IMMT
ING5
KAT5
KAT7
KATNBL1
KBTBD7
KPNA2
LRIF1
LUC7L2
MPP3
MRPS9
MSGN1
NAP1L5
NDUFB9
NEUROD1
NIPSNAP3A
NOD2
NOP53
PABPC4
PCM1
PDCD7
PFDN1
PKN1
PPID
PPOX
PPP1R18
PRPF31
PSMD11
RER1
RHPN1
RIF1
RPS10
RPS25
SCNM1
SNAPIN
SRSF4
STX5
TAF1D
TBP
TIMM17A
TNNT1
TNNT3
TOMM20
TSPYL1
UTP3
VIM
ZFP1
ZMAT2
ZNF124
ZNF20
ZNF24
ZNF33B
ZNF490
ZNF572
ZNF575
ZNF648
ZNF691
ZNF835
4 interacting genes:
COPS5
HAP1
HNRNPD
IMMT
Entrez ID
9001
5498
HPRD ID
02972
02953
Ensembl ID
ENSG00000173805
ENSG00000143224
Uniprot IDs
P54257
P50336
PDB IDs
3NKS
4IVM
4IVO
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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