TXNDC9 and GIT1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TXNDC9	GIT1
Description		thioredoxin domain containing 9	GIT ArfGAP 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol Midbody	Mitochondrion Cytosol Focal Adhesion Membrane Calyx Of Held
	Molecular Function	Protein Binding Cadherin Binding	GTPase Activator Activity Protein Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Biological_process	Intramembranous Ossification Brain Development Locomotory Behavior Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Cytokinesis Negative Regulation Of Interleukin-1 Beta Production Positive Regulation Of GTPase Activity Cell Redox Homeostasis Negative Regulation Of Glycolytic Process Ephrin Receptor Signaling Pathway Neuron Development Motor Learning Cellular Response To Lipopolysaccharide Presynaptic Modulation Of Chemical Synaptic Transmission Negative Regulation Of Inflammatory Response To Wounding Regulation Of Synaptic Vesicle Exocytosis
Pathways			Ephrin signaling Ephrin signaling Activation of RAC1 downstream of NMDARs
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Heel bone mineral density ( 30598549)	Adult body size ( 32376654) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		27 interacting genes: C1orf94 C3orf62 CCDC172 CEP126 CEP76 CHD3 COG4 DYDC1 ELP1 EXOSC8 FEZ1 GIT1 IMMT KLF11 LZTS1 MAGEA6 MED22 MRPL12 MYOG PBX4 PICK1 PNMA1 PTN SETDB1 TEX9 TRIM27 ZNF655	52 interacting genes: ARHGEF6 ARHGEF7 BARD1 C8orf33 CCDC113 CDC42 CENPU CEP126 CHD3 DDX24 EIF6 ENTR1 GIT2 GRB2 GRK2 GRK3 GRK5 GRK6 HAP1 HMOX2 HTT KIF1A LAMTOR5 LPXN LRIF1 MAN2A2 NEK2 PAK3 PCLO PDPK1 PFDN1 PLCG1 PMF1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PTK2 PTPRZ1 PXN RAN RGS2 RIF1 SRC SRRT TAB1 TERF1 TGFB1I1 TRIB3 TXNDC9 WDR33 YWHAG
Entrez ID		10190	28964
HPRD ID		15592	06577
Ensembl ID		ENSG00000115514	ENSG00000108262
Uniprot IDs		O14530	Q59FC3 Q9Y2X7
PDB IDs
Enriched GO Terms of Interacting Partners?
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