NKIRAS1 and NFKBIB

Data Source:
HPRD (in vitro, in vivo)

		NKIRAS1	NFKBIB
Description		NFKB inhibitor interacting Ras like 1	NFKB inhibitor beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Endoplasmic Reticulum Cytosol	Nucleus Cytosol
	Molecular Function	GTPase Activity GTP Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	I-kappaB Kinase/NF-kappaB Signaling	Transcription, DNA-templated Signal Transduction Cytoplasmic Sequestering Of NF-kappaB Positive Regulation Of Transcription, DNA-templated Cellular Response To Lipopolysaccharide
Pathways		RIP-mediated NFkB activation via ZBP1 TAK1 activates NFkB by phosphorylation and activation of IKKs complex TRAF6 mediated NF-kB activation	Activation of NF-kappaB in B cells RIP-mediated NFkB activation via ZBP1 TAK1 activates NFkB by phosphorylation and activation of IKKs complex TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Intake of total sugars ( 31005972) Intelligence (MTAG) ( 29326435)
Interacting Genes		8 interacting genes: ACVR1 APP BMPR1B NFKBIA NFKBIB SMURF2 TGFBR1 XRCC2	43 interacting genes: APP BAK1 BTBD6 BTRC CDC25A CHUK CSNK2A1 CUL1 DNAJA3 ESR2 FHL3 GIT2 IKBKB IKBKG KPNA2 LRPPRC MCC MTIF2 NCOR2 NDUFB7 NFKB1 NFKB2 NFKBIA NGFR NKIRAS1 NKIRAS2 PDCD2 POLR1A POLR1B POLR1C POLR1D POLR1E POLR1G POLR2H POLR2L PPARG RASAL2 REL RELA RXRA SKP1 TSPAN1 VPS52
Entrez ID		28512	4793
HPRD ID		06841	07260
Ensembl ID		ENSG00000197885	ENSG00000104825
Uniprot IDs		Q9NYS0	G5E9C2 Q15653
PDB IDs
Enriched GO Terms of Interacting Partners?
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