HTATSF1 and SNRNP70

Data Source:
HPRD (in vivo)

		HTATSF1	SNRNP70
Description		HIV-1 Tat specific factor 1	small nuclear ribonucleoprotein U1 subunit 70
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U2-type Spliceosomal Complex U2 SnRNP	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	RNA Binding	RNA Binding MRNA Binding Protein Binding SnRNA Binding U1 SnRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II Viral Genome Replication Regulation Of DNA-templated Transcription, Elongation	MRNA Splicing, Via Spliceosome Regulation Of ATPase Activity Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Refolding Negative Regulation Of Chaperone-mediated Autophagy
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Systolic blood pressure ( 30224653)
Interacting Genes		19 interacting genes: APBB1 CCNT1 CDK9 CLK1 CSNK2A1 ERCC6 FEZ1 GTF2F2 HDAC6 POLR2A SF3A2 SNRNP70 SNRPB2 SRPK2 SRSF4 SUPT4H1 SUPT5H WBP4 ZNF512B	46 interacting genes: APP ARSF CASP3 CDC42 CDKL3 CEP63 CHERP CLK2 CRP CTDP1 DDX17 GEMIN2 GTPBP2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2
Entrez ID		27336	6625
HPRD ID		02282	01617
Ensembl ID		ENSG00000102241	ENSG00000104852
Uniprot IDs		O43719	A0A024QZD5 P08621 Q9UFS1
PDB IDs		2DIT 6N3D 6N3E 6N3F 6NSX 6Y50 6Y53 6Y5Q	2L5I 2L5J 3CW1 3PGW 4PJO 4PKD 6QX9
Enriched GO Terms of Interacting Partners?
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