FBXO25 and DYRK3

Data Source:
BioGRID (enzymatic study)

		FBXO25	DYRK3
Description		F-box protein 25	dual specificity tyrosine phosphorylation regulated kinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex	Pericentriolar Material Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Cytoplasmic Stress Granule Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding
	Biological Process	Protein Ubiquitination	Protein Phosphorylation Cell Cycle Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Erythrocyte Differentiation Nuclear Speck Organization Stress Granule Disassembly Negative Regulation Of Apoptotic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Cell Division Regulation Of Cellular Response To Stress Positive Regulation Of Cell Cycle G2/M Phase Transition Organelle Disassembly Regulation Of TORC1 Signaling
Pathways
Drugs
Diseases
GWAS		Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)	Mean corpuscular volume ( 32888494)
Interacting Genes		82 interacting genes: ANKRD13A APLF AXL BMX BRME1 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GRK2 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ILRUN ING3 IRS1 JHY KDR KRT8 LMCD1 LUC7L MAT2B NKX2-5 NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TBX5 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1	4 interacting genes: FBXO25 GORASP2 NEDD4L PRNP
Entrez ID		26260	8444
HPRD ID		16439	04607
Ensembl ID		ENSG00000147364	ENSG00000143479
Uniprot IDs		A0A024QZ88 Q8TCJ0	O43781
PDB IDs			5Y86
Enriched GO Terms of Interacting Partners?
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